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个人简介
Experienced lab chemist and data scientist, I specialised in the field of drug discovery and design. I have explored small molecules, natural products and peptides as templates. My current research interests lie at the crossroads between protein engineering, drug discovery and artificial intelligence.
I contributed to several drug discovery programs involving multiple public-private partnerships in interdisciplinary environments across the globe: French National Scientific Research Centre CNRS teaming with Laboratoires Pierre Fabre (France), Institute of Molecular Bioscience at the University of Queensland (Australia) in collaboration with biotech subsidiary Noscira (Spain), with pharma giant Pfizer (USA), and the Pharmacy Australian Centre of Excellence PACE at the University of Queensland alongside biotech company Protagonist (Australia).
I am well-versed in analytical chemistry, solid-phase peptide synthesis, biological screenings as well as computational chemistry. We applied these techniques to therapeutic targets (kinases, GPCRs, transcription factors) in application to medical unmet needs: cancer treatments, type 2 diabetes, neurodegenerative disorders, neglected diseases (malaria, leishmania), and antibiotic resistance.
Alongside my laboratory abilities, I developed passion and skills in advanced statistics, machine learning and data visualisation to capture knowledge from medium-large datasets and make data-driven decisions. I have participated in several Health Hack weekends and massive online courses.
Since 2017, I am leading a research laboratory at the Center for Research and Advanced Studies (Cinvestav), where we focus on the discovery and design of bioactive peptides merging protein engineering, bioinformatics and artificial intelligence.
I am actively looking for an environment that shares interests in this thrilling research field.
研究兴趣
论文共 35 篇作者统计合作学者相似作者
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Mariana D. C. Aguilera-Puga,Fabien Plisson
SCIENTIFIC REPORTSno. 1 (2024): 11995-11995
Mariana D C Aguilera-Puga,Natalia L Cancelarich,Mariela M Marani,Cesar de la Fuente-Nunez,Fabien Plisson
Methods in molecular biology (Clifton, N.J.) (2024): 329-352
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2024): 1339285-1339285
Victor Daniel Aldas-Bulos,Fabien Plisson
DIGITAL DISCOVERYno. 4 (2023): 981-993
DIGITAL DISCOVERYno. 5 (2023): 1494-1505
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