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个人简介
Fátima Milhano dos Santos received her BSc and MSc degrees in Biochemistry from the University of Beira Interior (UBI) in 2010 and 2012, respectively, and was awarded in 2013 for the best ranking in the MSc degree (supported by UBI and Frulact S.A). In 2020, she received her Ph.D. in Biochemistry from the same institution with the project “Human vitreous proteome in vitreoretinal diseases" granted with an FCT doctoral fellowship (SFRH/BD/112526/2015). This Ph.D. project was integrated into a project financed by Novartis Farma and aimed to find vitreous biomarkers in several vitreoretinal diseases. Several straightforward proteomics approaches (gel-based and gel-free) were developed for an in-depth analysis of vitreous humor proteome in diabetic retinopathy, retinal detachment, and age-related macular degeneration. Besides providing fundamental information about the pathways changed in these pathologies, this work allowed the validation of 26 potential biomarkers that could be used for the prognosis of the patient's disease evolution and/or to predict the proper response to treatment. The challenging nature of this project motivated her attendance of several training courses in the proteomics field and two short-term internships (1 month in 2014 and 3 months in 2019) at the Proteomics Facility of Spanish National Biotechnology Centre (CNB-CSIC, Madrid, Spain). She participated in several financed projects as a research fellow and team member at the Health Sciences Research Centre (CICS-UBI, Covilhã, Portugal) and Mediterranean Institute for Agriculture, Environment, and Development (MED-UE, Évora, Portugal). During the 2012-2020 period in UBI, she participated in the teaching of practical classes, in the supervising/tutoring of several master’s degree students, and in the organization of scientific dissemination events (e.g., II International Congress in Health Sciences Research). She was also a member of the Doctoral Students Committee (CAD-CICS-UBI) (2016-2017) and participated actively in the conception of the new proteomics laboratory in CICS-UBI through the implementation of techniques such as two-dimensional electrophoresis and protein analysis by MALDI-TOF/TOF and LC-MS/MS. Since 2020, she is a member of the Functional Proteomics laboratory (CNB-CSIC) led by Fernando Corrales. In the context of the ongoing COVID-19 pandemic, she is characterizing the molecular interaction of SARS-CoV-2 with A549 pulmonary epithelial cells transfected with the ACE2 to identify new therapeutic targets for antiviral drug repurposing and/or discovery. This project is coordinated with national and international initiatives such as the “Global Health” Interdisciplinary Platform (PTI-CSIC), COVID-19 MS-Coalition, and Human Proteome Organization (HUPO). She published 12 scientific papers and 3 conference papers, the majority as a first author, with 92 citations (h-index: 5) according to SCOPUS and 165 (h-index: 8) according to google scholar. She also participated in dozens of conferences with oral communications (8 international and 11 national) and poster communications (14 international and 12 national) in the last years. She also regularly does peer review for several scientific journals (MDPI, Nature Publishing Group).
研究兴趣
论文共 30 篇作者统计合作学者相似作者
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Talanta (2024): 125988-125988
Laura Guerrero,Lorena Carmona-Rodriguez,Fatima Milhano Santos,Sergio Ciordia, Luiz Stark,Loreto Hierro, Pablo Perez-Montero,David Vicent,Fernando J. Corrales
BIOFACTORS (2024)
João Ribeiro, Marco Â. Luís, Bruno Rodrigues,Fátima Milhano Santos,Joana Mesquita,Renato Boto,Cândida Teixeira Tomaz
Gelsno. 3 (2024): 198
Joana Mesquita,Fatima Milhano Santos,Joao Paulo Sousa, Sara Vaz-Pereira,Paulo Tavares-Ratado, Arminda Neves, Rita Mesquita, Candida Teixeira Tomaz
CUREUS JOURNAL OF MEDICAL SCIENCEno. 2 (2024): e54862-e54862
Andrea Figuer Rubio,Fátima Milhano Santos,Sergio Ciordia,Gemma Valera, Beatriz Martín-Jouve, Juan Pablo Hernández,Guillermo Bodega,Manuel Ramírez Chamond,Julia Carracedo,Matilde Alique
Nephrology Dialysis Transplantationno. Supplement_1 (2024)
Andrea Figuer,Fátima M. Santos,Sergio Ciordia,Gemma Valera, Beatriz Martín-Jouve, Juan Pablo Hernández-Fonseca,Guillermo Bodega,Noemí Ceprián,Rafael Ramírez,Julia Carracedo,Matilde Alique
Life Sciences (2024): 122810-122810
Clinical Proteomicsno. 1 (2024): 1-17
Alejandra Isabel Navarro Leon,Marta Munoz,Natalia Iglesias,Cristina Blanco-Vazquez,Ana Balseiro,Fatima Milhano Santos,Sergio Ciordia,Fernando J. Corrales,Tania Iglesias,Rosa Casais
Journal of proteome research (2023)
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