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Fiona Powrie is Director of the Kennedy Institute of Rheumatology and the Translational Gastroenterology Unit at the University of Oxford. Her research interests include characterising the interaction between the intestinal microbiota and the host immune system and how this mutualistic relationship breaks down in inflammatory bowel disease.
Her work has identified the functional role of regulatory T cells in intestinal homeostasis and shed light on their development and mechanism of action. She has also shown that both adaptive and innate immune mechanisms contribute to intestinal inflammation and identified the IL-23 pathway as a pivotal player in the pathogenesis of chronic intestinal inflammation. Her current work seeks to translate findings from model systems into the clinic in inflammatory bowel disease patients.
Fiona received the Ita Askonas Award from the European Federation of Immunological Societies for her contribution to immunology in Europe and the Louis-Jeantet Prize for Medicine in 2012. She was elected a Fellow of the Royal Society in 2011, EMBO in 2013 and the Academic of Medical Sciences in 2014.
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论文共 244 篇作者统计合作学者相似作者
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Marisol Alvarez-Martinez, Luke S. Cox,Claire F. Pearson,William J. Branchett,Probir Chakravarty,Xuemei Wu, Hubert Slawinski,Alaa Al-Dibouni, Vasileios A. Samelis,Leona Gabrysova,Simon L. Priestnall,Alejandro Suarez-Bonnet,
NATURE IMMUNOLOGYno. 5 (2024): 886-901
India Brough,Kelsey Thompson, Ciara Latore,Frank Penkava, Chelsea Regan,Claire Pearson,Hui Shi,Anna Ridley,Davide Simone,Lilian Lam,Samuel Bullers, Caroline Moussa,
Discovery Immunology (2024)
Naturepp.1-9, (2024)
Marisol Alvarez-Martinez,Luke S. Cox,Claire F. Pearson,William J. Branchett,Probir Chakravarty,Xuemei Wu, Hubert Slawinski,Alaa Al-Dibouni, Vasileios A. Samelis,Leona Gabryšová,Simon L. Priestnall,Alejandro Suárez-Bonnet,
bioRxiv (Cold Spring Harbor Laboratory) (2023)
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Kelsey N. S. Thompson,Kevin S. E. Bonham,Nicholas E. J. Ilott,Graham J. Britton, Paula J. Colmenero,Samuel J. J. Bullers,Lauren J. McIver,Siyuan H. Ma,Long H. Nguyen,Andrew Filer, India Brough,Claire Pearson,
SCIENCE TRANSLATIONAL MEDICINEno. 706 (2023): eabn4722-eabn4722
Journal of Immunologyno. 1 (2023): 218.22-218.22
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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medRxivno. 5 (2022): 916-+
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