基本信息
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Career Trajectory
Bio
Research field:
The interest of our group is to investigate how signaling networks control key biological processes in physiological and pathological conditions.
Our main interest is focused on Acute Myeloid Leukemia (AML). Thanks to the AIRC grant, we are currently focusing on the mechanisms driving drug resistance in FLT3-dependent AML.
We apply a multidisciplinary strategy, where we combine high-throughput approaches, including mass spectrometry-based proteomics, phosphoproteomics and affinity proteomics, as well as transcriptomics with bioinformatic strategies to obtain predictive models of cancer cells.
We also interested to elucidate the connection between signaling pathways and metabolism control.
AREA OF EXPERTISE
Mass spectrometry-based proteomics, phosphoproteomics and interactomics
Systems biology
Large scale statistical data analysis
Signal Transduction
Cancer pathways
Metabolism
Beta cells biology
Phosphorylation
Protein-protein interaction
Molecular genetics
Project planning and budgeting
Problem solving
Collaboration establishment
Honors and awards
Awarded with the EMBO Long-Term Fellowship from the European Molecular Biology Organization.
Ad hoc peer reviewer for manuscripts submitted to: Molecular & Cellular Proteomics, Scientific Reports, FEBS Journal, FEBS Letters, PLOS one, Oncotarget, Methods, Journal of Biological chemistry, Frontiers Genetics.
Manuscript selected for the cover image of the March issue 2016 of the Cell Systems journal.
Poster prize at the “Translating Diabetes” meeting at the EMBL, Heidelberg, 2014.
Qualification as a Professional Biologist.
Awarded with 5000 euro prize for the highest exam scores obtained during the bachelor and master degrees.
The interest of our group is to investigate how signaling networks control key biological processes in physiological and pathological conditions.
Our main interest is focused on Acute Myeloid Leukemia (AML). Thanks to the AIRC grant, we are currently focusing on the mechanisms driving drug resistance in FLT3-dependent AML.
We apply a multidisciplinary strategy, where we combine high-throughput approaches, including mass spectrometry-based proteomics, phosphoproteomics and affinity proteomics, as well as transcriptomics with bioinformatic strategies to obtain predictive models of cancer cells.
We also interested to elucidate the connection between signaling pathways and metabolism control.
AREA OF EXPERTISE
Mass spectrometry-based proteomics, phosphoproteomics and interactomics
Systems biology
Large scale statistical data analysis
Signal Transduction
Cancer pathways
Metabolism
Beta cells biology
Phosphorylation
Protein-protein interaction
Molecular genetics
Project planning and budgeting
Problem solving
Collaboration establishment
Honors and awards
Awarded with the EMBO Long-Term Fellowship from the European Molecular Biology Organization.
Ad hoc peer reviewer for manuscripts submitted to: Molecular & Cellular Proteomics, Scientific Reports, FEBS Journal, FEBS Letters, PLOS one, Oncotarget, Methods, Journal of Biological chemistry, Frontiers Genetics.
Manuscript selected for the cover image of the March issue 2016 of the Cell Systems journal.
Poster prize at the “Translating Diabetes” meeting at the EMBL, Heidelberg, 2014.
Qualification as a Professional Biologist.
Awarded with 5000 euro prize for the highest exam scores obtained during the bachelor and master degrees.
Research Interests
Papers共 59 篇Author StatisticsCo-AuthorSimilar Experts
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eLife (2024)
Linda Cerofolini,Enrico Ravera, Christian Fischer, Andrea Trovato,Francesca Sacco,Wolf Palinsky, Gabriella Angiuoni,Marco Fragai,Fabio Baroni
Analytical chemistryno. 24 (2023): 9199-9206
Francesca Sacco,Giorgia Massacci, V Rezelj Veronica,Valeria Bica,Sara Latini, Thomas Fischer,Dimitrios Mougiakakos,Martin Böttcher,Livia Perfetto,Natalie Krahmer,Felix Klingelhuber, Michela Pugliese
HemaSphereno. S3 (2023): e310578d-e310578d
BRITISH JOURNAL OF CANCERno. 11 (2023): 1707-1716
Leukemiano. 5 (2023): 1151-1155
Science Advancesno. 35 (2022): eabo1215-eabo1215
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