基本信息
浏览量:44
职业迁徙
个人简介
My group investigates the basic principles underlying animal cell morphogenesis. A precise control of cellular shape is key to cell physiology, and cell shape deregulation is at the heart of many pathological disorders including cancer. Yet, how cells regulate their own shape remains poorly understood. We investigate this question taking an interdisciplinary approach combining molecular and cell biology, quantitative imaging, mechanical measurements and physical modelling.
We particularly focus on the cell cortex, a thin actomyosin network that lies under the plasma membrane and determines the shape of most animal cells. The cortex enables the cell to resist externally applied stresses and to exert mechanical work. As such, it plays a role in normal physiology during events involving cell deformation such as cell division and migration, and in the pathophysiology of diseases such as cancer where cell shape is often deregulated.
We particularly focus on the cell cortex, a thin actomyosin network that lies under the plasma membrane and determines the shape of most animal cells. The cortex enables the cell to resist externally applied stresses and to exert mechanical work. As such, it plays a role in normal physiology during events involving cell deformation such as cell division and migration, and in the pathophysiology of diseases such as cancer where cell shape is often deregulated.
研究兴趣
论文共 84 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Julie A. Theriot,Anne Simonsen,Iva Tolić,Manuel D. Leonetti,Satyajit Mayor,Patricia Bassereau,Ewa K. Paluch, Jiahuai Han,Markus W. Covert,Noboru Mizushima, Samara Reck-Peterson,Andreas Strasser,
Cellno. 2 (2024): 219-224
Julie A. Theriot,Anne Simonsen, Iva Tolic, Manuel D. Leonetti,Satyajit Mayor, Patricia Bassereau,Ewa K. Paluch,Jiahuai Han,Markus W. Covert,Noboru Mizushima, Samara Reck-Peterson,Andreas Strasser,
CELLno. 2 (2024): 219-224
引用0浏览0引用
0
0
Julie A Theriot,Anne Simonsen,Iva Tolić,Manuel D Leonetti,Satyajit Mayor,Patricia Bassereau,Ewa K Paluch, Jiahuai Han,Markus W Covert,Noboru Mizushima, Samara Reck-Peterson,Andreas Strasser,
Cellno. 2 (2024): 219-224
bioRxiv (Cold Spring Harbor Laboratory) (2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn