基本信息
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Career Trajectory
Bio
The main focus of research has been on genetic predisposition to breast cancer and type 2 neurofibromatosis. I have developed a national clinical and molecular database for NF2 which has become an invaluable research tool being the largest such database worldwide. We have also collected the largest number of breast cancer families UK wide which has meant we are the biggest contributor to a number of national breast cancer research initiatives (FBOC, EMBRACE, MARIBS, IMPACT). The focus of my research is moving away from clinical pattern recognition and gene identification towards cancer prevention. With Professor Howell we are setting up a major programme for breast cancer prevention in Manchester. This involves development of surrogate markers. As our clinical work has provided the largest number of families with known high risk breast cancer gene defects we are likely to lead prevention strategies in the UK from now on. Use of high tech MRI will also allow the proper assessment of non-surgical intervention in the treatment of benign brain tumours, with work in collaboration with Professor Jackson.
Research Interests
Papers共 1466 篇Author StatisticsCo-AuthorSimilar Experts
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Genetics in Medicineno. 9 (2024): 101172-101172
Kelly Metcalfe,Jan Lubinski,Jana Soukupová,Rinat Bernstein-Molho, Mina Lee,Evans Gareth,Arvids Irmejs,Robert Fruscio, Cynthia Villareal Garza,Joanne Ngeow, Jennifer Plichta,Rinat Yerushalmi,
Cancer Researchno. 9_Supplement (2024): GS02-04
Hereditary Cancer in Clinical Practiceno. 1 (2024): 1-12
Journal of Medical Geneticspp.jmg-2023, (2024)
medRxiv : the preprint server for health sciences (2024)
CLINICAL TRIALSno. 1 (2024): 40-50
Familial Cancerpp.1-9, (2024)
Mary Pegington,John Belcher,Emma Barrett, Pawandeep Virpal,Anthony Howell,D. Gareth Evans,Michelle Harvie
BJC Reportsno. 1 (2024): 1-10
medrxiv(2024)
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Author Statistics
#Papers: 1473
#Citation: 109713
H-Index: 153
G-Index: 295
Sociability: 9
Diversity: 4
Activity: 414
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