基本信息
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Bio
Dr. Chang's laboratory studies intestinal microbes and viruses (the microbiome), particularly as they relate to health, digestive diseases (IBD) and other immune- and metabolic-related disorders. This relationship is fundamental to our health and, when perturbed, the consequences can be catastrophic. The emergence of “Western” disorders like diabetes, obesity, metabolic syndrome, cancer and autoimmune disorders over the past century may be related to large shifts in the composite human microbiome caused by changes in the environment and life styles. In genetically susceptible individuals, these factors can potentially trigger events that disturb immune and metabolic homeostasis, initiating the development of disease. His efforts are therefore directed towards gaining a better understanding of what factors are involved in the selection and assembly of intestinal microbes, and how they can be used to reshape the enteric microbiome to prevent and treat disease.
Research Interests
Papers共 490 篇Author StatisticsCo-AuthorSimilar Experts
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Orlando DeLeon, Mora Mocanu,Candace M. Cham,Alan Tan, Hugo Ceccato,Ashley M. Sidebottom, John J. Colgan,Marissa St. George,Zhilu Xu,Siew C. Ng,Francis K. Chan,Hein M. Tun,
Gastroenterologyno. 5 (2024): S-119
Molecular Neurodegenerationno. 1 (2024): 1-26
CELLno. 5 (2024): 1206-1222.e16
Gastroenterologyno. 5 (2024): S-857
Ye Peng,Jie Zhu,Shilan Wang,Yingzhi Liu, Xin Liu,Orlando DeLeon,Wenyi Zhu,Zhao Shilin,Suisha Liang, Hang Li, Brian W. Ho,Jessica Y. Ching,
Gastroenterologyno. 5 (2024): S-615
Aretha Fiebig,Matthew K. Schnizlein, Selymar Pena-Rivera,Florian Trigodet,Abhishek Anil Dubey, Miette K. Hennessy,Anindita Basu,Sebastian Pott,Sushila Dalal,David Rubin,Mitchell L. Sogin,A. Murat Eren,
MBIOno. 1 (2024): e0283023-e0283023
Tanner G Richie, Hallie Wiechman, Carson Ingold,Leah Heeren,Abigail Kamke,Sophia Pogranichniy,Kourtney Monk, Trey Summers,Qinghong Ran,Soumyadev Sarkar,Brandon L Plattner,Ashley M Sidebottom,
bioRxiv : the preprint server for biology (2024)
Inflammatory bowel diseases (2024)
Nature Chemical Engineeringno. 1 (2024): 73-86
Shilan Wang,Yingzhi Liu,Wing Hung Tam,Jessica Y.L. Ching,Wenye Xu,Shuai Yan, Biyan Qin, Ling Lin, Ye Peng, Jie Zhu,Chun Pan Cheung,Ka Long Ip,
Cell Host & Microbeno. 7 (2024): 1192-1206.e5
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Author Statistics
#Papers: 492
#Citation: 30068
H-Index: 86
G-Index: 166
Sociability: 8
Diversity: 3
Activity: 80
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