基本信息
views: 5
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
I have been working in the immunology field for nearly a decade, with relevant research experience at the undergraduate, postbaccalaureate, graduate, and professional levels. During my undergraduate education I worked on studies relating to the molecular pathogenesis of Sjögren’s syndrome, an autoimmune disorder. As a post-graduate, I sought the opportunity to expand my academic research experience as a research technician at the Ohio State University under the mentorship of Drs. John C. Byrd, Jason Dubovsky, and Natarajan Muthusamy. My work at Ohio State focused on chronic lymphocytic leukemia, checkpoint inhibition, acquired drug resistance, and bone marrow transplant-associated graft-versus-host disease (GVHD), especially in relation to Tec kinase inhibitors such as ibrutinib. Working with Dr. Dubovsky, I helped to demonstrate ibrutinib’s efficacy in pre-clinical models of chronic GVHD. This work was seminal in the field and eventually led to the acceptance of ibrutinib as the first FDA-approved therapy for chronic GVHD.
Upon leaving Ohio State in 2016, I began my PhD at the University of Kentucky. In July of 2017, I joined the lab of Gerhard Hildebrandt, MD, a researcher studying translational therapies in GVHD. There, my projects have focused on chronic GVHD treatment and etiology, especially in regards to induction of fibrosis by mast cells and treatment of chronic GVHD with 2nd generation Tec kinase inhibitors. I successfully defended my PhD dissertation in August 2020.
Much of my research output has focused on disease states characterized by pathological immunity and this has helped to shape my research interests for the future. I would like to further explore the cross-talk between the innate and adaptive immune system, with a focus on innate and adaptive mechanisms by which the immune system balances autoimmunity and homeostasis.
Research Interests
Papers共 25 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Transplantation and cellular therapyno. 10 (2023): 608.e1-608.e9
Reena Kumari,Audrey Law, Bara Naji Hamdi Alzghoul,Ethan Strattan, Timothy Huang,Luke Moe, Senthilnathan Palaniyandi, Gerhard C. Hildebrandt
Transplantation and Cellular Therapyno. 3 (2022): S316-S316
International journal of molecular sciencesno. 5 (2021): 2385
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn