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个人简介
Since he joined the IQM, Dr. Ernesto Quesada was integrated into the research group “Nucleosides and Analogues as a source of bioactive molecules” (IQM-GN), where he has carried out research focused on the discovery of highly added-value molecules with potential biological activity directed to treat diseases through innovative strategies. This activity has been carried out again in a multidisciplinary environment, where his responsibilities lies on synthetic aspects (design, synthesis, isolation and characterization of organic compounds) directed to provide new molecular entities to be studied by the network of collaborators committed with the research group. It must be highlighted the key role of Prof. F. Gago (UAH; molecular modelling) and Profs. J. Balzarini, D. Schols and J. Neyts, from the Rega Institute for Medical Research-Catholic University of Leuven (Belgium), involved in the biological evaluation of the synthesized compounds.
In the last decade Dr. Quesada has participated in different projects, emphasizing his involvement in two main research subjects: a) the search for chemotherapeutic agents directed to inhibit the entry of prevalent (HIV) or emerging viral pathogens (Flaviviruses (Dengue, WNV, Zika), enteroviruses (EV71) or coronaviruses (SARS-CoV2) in close collaboration with Dr. Ana San Félix and Maía Jesús Pérez (members of the IQM-GN research group); b) the role of TLR4 receptor inhibition in different pathologies, in collaboration with the research group of Prof. C. Goicoechea and Dr. Miguel Ángel Martínez García (Dpt. of Pharmacology, Universidad Rey Juan Carlos-URJC, Madrid).
Dr. Ernesto Quesada has co-authored >30 research articles in international peer-reviewed journals (75% indexed in Q1; 20% indexed in Q2). The ResearcherID-Publons (B-7823-2008) and ORCID (0000-0001-6886-0523) codes allow direct access to the whole list and details about the scientific production and statistic indicators of the quality of the contributions. He has also presented or co-authored more than 50 communications to national and international meetings and participated in more than 20 national competitive funded projects (two of them as principal investigator), as well as 2 research contracts. He is member of two Associated Research Units (unidades asociadas) between IQM-CSIC and the Universidad Rey Juan Carlos (URJC, Madrid) and the Universidad de Alcalá (UAH, Madrid), respectively.
In the last decade, Dr. Quesada has supervised more than 20 people at different levels (short-term student internships or guided practices of laboratory technicians) and directed several Trabajos Fin de Grado (TFG) and Trabajos Fin de Máster (TFM; MSc project). It must be highlighted that he has supervised 4 hired laboratory technicians (granted by 2-year contracts each one) and 2 hired postdoctoral researchers.
Dr. Quesada is regular reviewer of international scientific journals and he has been member of organising committees of scientific meetings. He has also performed complementary non- research activities such as teaching in Master programs (UAM and UCM), postgraduate and specialization courses (CSIC) as well as outreach activities (conferences, workshops, etc.).
研究兴趣
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Visitacion Lopez-Miranda Gonzalez,Antonio Gonzalez, Silvia Flaj, Victor Fernandez-Cabello,Raquel Hernanz, Maria-Jesus Alonso,Ernesto Quesada,Esperanza Herradon,Visitacion Lopez-Miranda
CLINICAL SCIENCE (2023)
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Marta García-Zarandieta,Ernesto Quesada,María I Martínez-Jiménez, Cristina V Newnes, Victor Fernández-Cabello,Yanira Sáez-Álvarez,Ana-Belén Blázquez,Estela Escribano-Romero,Juan-Carlos Saiz,Carmen Del Águila,Miguel A Martín-Acebes,María-Jesús Pérez-Pérez,
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie (2022): 112986-112986
Frontiers in Natural Product Chemistry: Volume 7Frontiers in Natural Product Chemistrypp.31-109, (2021)
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