基本信息
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Bio
The Fraenkel laboratory is developing computational and experimental approaches to search for new therapeutic strategies for diseases. New experimental methods make it possible to measure cellular changes across the genome and proteome. These technologies include genome-wide measurements of transcription, of protein-DNA interactions (ChIP-Seq), of genetic interactions, and of protein modifications. Each data source provides a very narrow view of the cellular changes. However, by computationally integrating these data the group can reconstruct signaling pathways and identify previously unrecognized regulatory mechanisms that contribute to the etiology of disease and may provide new approaches for treatment.
Current projects focus on the study of cancer, neurodegenerative diseases, and diabetes.
Current projects focus on the study of cancer, neurodegenerative diseases, and diabetes.
Research Interests
Papers共 189 篇Author StatisticsCo-AuthorSimilar Experts
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crossref(2024)
Mohammad Dehestani,Velina Kozareva, Cornelis Blauwendraat,Ernest Fraenkel,Thomas Gasser, Vikas Bansal
Molecular Brainno. 1 (2024): 1-10
crossref(2024)
Clinical cancer research : an official journal of the American Association for Cancer Researchno. 9 (2024): 1889-1905
Mohammad Dehestani,Wiebke Kessler, Nasser Karmali, Wenhua Sun,Stanislav Tsitkov,Ashutosh Dhingra,Salvador Rodriguez-Nieto, Julia Tietz,David Schafflick,Noemia Fernandes,Ernest Fraenkel,Thomas Gasser,
biorxiv(2024)
crossref(2024)
crossref(2024)
Natureno. 7994 (2024): 377-384
crossref(2024)
Matthew J Leventhal,Camila A Zanella, Byunguk Kang,Jiajie Peng,David Gritsch,Zhixiang Liao,Hassan Bukhari,Tao Wang,Ping-Chieh Pao, Serwah Danquah,Joseph Benetatos,Ralda Nehme,
bioRxiv : the preprint server for biology (2024)
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Author Statistics
#Papers: 184
#Citation: 19628
H-Index: 51
G-Index: 123
Sociability: 7
Diversity: 3
Activity: 109
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