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个人简介
The Fraenkel laboratory is developing computational and experimental approaches to search for new therapeutic strategies for diseases. New experimental methods make it possible to measure cellular changes across the genome and proteome. These technologies include genome-wide measurements of transcription, of protein-DNA interactions (ChIP-Seq), of genetic interactions, and of protein modifications. Each data source provides a very narrow view of the cellular changes. However, by computationally integrating these data the group can reconstruct signaling pathways and identify previously unrecognized regulatory mechanisms that contribute to the etiology of disease and may provide new approaches for treatment.
Current projects focus on the study of cancer, neurodegenerative diseases, and diabetes.
Current projects focus on the study of cancer, neurodegenerative diseases, and diabetes.
研究兴趣
论文共 175 篇作者统计合作学者相似作者
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Cristina Guarducci,Agostina Nardone,Douglas Russo, Zsuzsanna Nagy, Capucine Heraud,Albert Grinshpun, Qi Zhang,Allegra Freelander, Matthew Joseph Leventhal, Avery Feit, Gabriella Cohen Feit, Ariel Feiglin,
Clinical cancer research : an official journal of the American Association for Cancer Research (2024)
Natureno. 7994 (2024): 377-384
Matthew J Leventhal, Camila A Zanella, Byunguk Kang,Jiajie Peng,David Gritsch,Zhixiang Liao,Hassan Bukhari,Tao Wang,Ping-Chieh Pao, Serwah Danquah, Joseph Benetatos,Ralda Nehme,
bioRxiv : the preprint server for biology (2024)
Maxwell P. Gold, Winnie Ong, Andrew M. Masteller,David R. Ghasemi, Julie Anne Galindo,Noel R. Park,Nhan C. Huynh, Aneesh Donde,Veronika Pister, Raul A. Saurez,Maria C. Vladoiu,Grace H. Hwang,
Nature Communicationsno. 1 (2024): 270-270
MUSCLE & NERVEno. 1 (2024): 40-47
Nature Communicationsno. 1 (2024): 269-269
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