My translational and clinical research focus is pediatric brain tumors. My lab investigates 1) the mechanism of oncolytic viral immunotherapy for the treatment of solid tumor and disseminated medulloblastoma, and 2) the role of Abelson family kinases (ABL1 and ABL2) in the promotion of leptomeningeal dissemination of pediatric brain tumors.

My clinical research focuses on 1) using a novel peptide vaccine to target CMV antigens to treat children with recurrent medulloblastoma and malignant glioma and 2) using oncolytic poliovirus to treat children with recurrent malignant glioma.