Research Interests
Molecular analysis of cancer pathogenesis; βeta-catenin-dependent Wnt signaling; transgenic and knockout mouse models of colon cancer; miRNAs and cancer; CDX2 homeobox gene function.
The research in the Fearon laboratory seeks to address the means by which specific oncogene and tumor suppressor gene defects contribute to the pathogenesis of colon and other cancers and to develop novel strategies for early detection and treatment of colorectal adenomas and carcinomas.