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Bio
I graduated with a First-Class Honours (B.A.) degree in neuroscience from Trinity College Dublin (TCD) in 2014 and an M.Sc. in Immunology from the Trinity Biomedical Sciences Institute in 2015. My doctoral research assessed the anti-inflammatory and neuroprotective efficacy of pharmacologically targeting glial beta2-adrenoceptors in Parkinson's disease. My research identified a role for the beta2-AR in regulating inflammation in experimental Parkinson's disease and demonstrated that formoterol, a long-acting highly selective beta2-AR agonist and clinically approved asthma drug, may be repurposed as a potential anti-Parkinsonian treatment. I was awarded my PhD from the School Pharmacy & Pharmaceutical Sciences, TCD in 2019. I did my first postdoc in in the Trinity College Institute of Neuroscience, where I investigated neural activity within the claustrum of an experimental rodent model of Parkinson's disease. I then started postdoctoral research on sex-differences in aging and Alzheimer's disease (AD) with a focus on microglia and neuroinflammation in the hippocampus of APP/PS1 transgenic mouse models of AD, and in post-mortem human AD brain samples (2020). My current research investigates the potential link between neonatal infection with the gram-negative bacteria Bordetella pertussis and the development of autism spectrum disorder (ASD) later in life.
Research Interests
Papers共 10 篇Author StatisticsCo-AuthorSimilar Experts
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Eoin O'Neill,Éadaoin W Griffin, Ruairi O'Sullivan,Carol Murray,Lucy Ryan,Justin Yssel,Andrew Harkin,Colm Cunningham
Brain, behavior, and immunity (2020): 357-368
British journal of pharmacologyno. 2 (2019): 282-297
Brain, behavior, and immunity (2018): 456-469
International Journal of Technology Management (2014)
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#Papers: 8
#Citation: 163
H-Index: 6
G-Index: 8
Sociability: 3
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