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Associate Professor Emma Hamilton-Williams' career focuses on understanding how immune tolerance is disrupted leading to the development of type 1 diabetes. Her laboratory now focuses on developing an immunotherapy for type 1 diabetes as well as understanding the role of the gut microbiota in as a potential trigger for type 1 diabetes. Her laboratory is using nanoparticle technology to deliver an immunotherapy that specifically tolerises the immune cells that cause type 1 diabetes and is working towards a first-in -human trial of this approach. She uses state-of-the-art protein sequencing techniques to probe how disturbances in the gut microbiota of children with type 1 diabetes impacts the function of the gut and the pancreas. She recently currently conducted a clinical trial of a microbiome-targeting dietary supplement aimed at restoring a healthy microbiome and immune tolerance with an ultimate aim of preventing type 1 diabetes.
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STAR protocolsno. 4 (2021): 100842
Anne-Sophie Bergot,Irina Buckle, Sumana Cikaluru, Jennifer Loaiza Naranjo,Casey Maree Wright,Guoliang Zheng,Meghna Talekar,Emma E Hamilton-Williams,Ranjeny Thomas
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