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Dr. Strehler's research focuses on the calcium pumps in the plasma membrane. These pumps are essential for the setting of cellular Ca2+ levels and are involved in calcium transport in the intestine and kidney, as well as in neuronal function. The lack or inappropriate function of these pumps has been linked to multiple clinical disorders, including age-related hearing loss, cardiovascular disease and Alzheimer's disease, among others.
Collaborative studies performed in Dr. Strehler's laboratory use a range of techniques, including those of recombinant DNA technology (PCR, mutagenesis and vector construction) and cell biology (confocal fluorescence microscopy and cell imaging) to study the basic mechanisms of calcium pump targeting and function in cultured cells.
Research Interests
Papers共 279 篇Author StatisticsCo-AuthorSimilar Experts
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REGULATION OF CA2+-ATPASES, V-ATPASES AND F-ATPASES (2016)
Science Signalingno. 364 (2015)
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