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We now know, thanks in part to her studies, that cervical cancer is caused by infection with high-risk types of HPV in almost all cases. Her most important contribution was a series of studies starting in the 1990s that linked infection with those high-risk HPV types that lead to cervical cancer with the causation of a subset of cancers of the head and neck, predominantly those in the rear part of the oral cavity, tonsils and the pharynx.
Furthermore, Elaine and her collaborators were one of the two groups to show that HPV-linked head and neck cancers had a much better prognosis than non-viral cancers associated with cigarette smoking and alcohol consumption, and should be considered a separate etiologic entity. HPV screening in head and neck cancer now is part of the routine diagnostic workup in clinical laboratories.
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Dohun Pyeon,Michael A. Newton,Paul F. Lambert,Johan A. den Boon, Srikumar Sengupta,Carmen J. Marsit,Craig D. Woodworth, Joseph P. Connor,Thomas H. Haugen,Elaine M. Smith,Karl T. Kelsey,Lubomir P. Turek,
crossref(2023)
Dohun Pyeon,Michael A. Newton,Paul F. Lambert,Johan A. den Boon, Srikumar Sengupta,Carmen J. Marsit,Craig D. Woodworth, Joseph P. Connor,Thomas H. Haugen,Elaine M. Smith,Karl T. Kelsey,Lubomir P. Turek,
crossref(2023)
crossref(2022)
user-5f163cde4c775ed682f575fe(2020)
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