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个人简介
Elaine DEL NERY is a former Postdoc research associate at the Curie Institute where she conducted biochemical and cell-based studies on cellular signaling pathways regulated by small GTPases (Bruno Goud's team - UMR144). Since then, she is in charge of the Biophenics Platform team which performs the design, development and implementation of drugs and siRNAs cell-based assays for image-based high-content screening applications on human cells. Her team supports academic and medical research teams in functional-genomic and chemical screening programs for improving biomarker discovery, pharmacological profiling and crug combinations studies in cancer and inflammatory diseases field. She has a solid expertise in developing cell-based screening assays to evaluate multiple biochemical and morphological parameters in cells, by tracking phenotypes at the cellular and sub-cellular levels under various perturbing conditions (chemical and siRNA collections). Her aim is to broaden novel opportunities to explore the high dimensionality of the phenotypic screening data and thus, contribute to the understanding of how biological pathways can be targeted for therapeutic intervention. She has B.SC. in BIOMEDICINE (Paulista Medical School, SP, Brazil) and have obtained a M.SC. IN BIOCHEMISTRY (1996 – 1998) and a PH.D. IN MOLECULAR BIOLOGY (1999 – 2000) working on peptide synthesis and enzymatic studies to determine mechanism of action of proteolytic enzymes. Main work was based on the screening of combinatorial chemical libraries for the development of enzyme inhibitors as potential leads for anti-infective and anti-tumour therapeutic drug development. She was a research fellow at the University of Colorado Health Sciences Center - School of Medicine, Denver, CO, USA (1998 – 1999) where contributed to work leading to the licensing of PC6A gene by GlaxoSmithKline as a target for novel HIV therapeutic drugs, supervised by Alex FRANZUSOFF Vice President of Research, GlobeImmune, Inc., CO, USA. Recent degrees includes medical bioethics achieved in 2017.
研究兴趣
论文共 84 篇作者统计合作学者相似作者
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NATUREno. 7999 (2024): E13-E13
Pierre Verrelle,Pierre Gestraud,Florent Poyer, Adele Soria,Sarah Tessier,Aurianne Lescure,Elodie Anthony,Maxime Corbe, Sophie Heinrich,Claire Beauvineau,Ludovic Chaput,Anton Granzhan,
Natureno. 7999 (2024): E13-E13
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Cancer Researchno. 5_Supplement (2023): P3-07
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