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My research field is molecular genetics of aging with current focus on the microRNAs and extracellular vesicles and high-density lipoprotein as the signal transduction agents that mediate the gene-lifestyle interactions, which I study using rodent models, cell experiments and human studies. Broadly speaking my research interests are in the biological aspects of aging, physical activity and their interaction, and associations with health. I use a wide range of the methods of molecular genetics including epigenetics, transcriptomics, proteomics, and microRNA/gene/protein expression studies as well as objective and subjective physical activity measurements, performance measurements, body composition assessments and structured questionnaires to get deeper understanding of the phenomena under investigation. The major aim is to improve understanding of detailed molecular and physiological mechanisms responsible for the maintenance of healthy interaction between muscle and other tissues while age is advancing.
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Papers共 91 篇Author StatisticsCo-AuthorSimilar Experts
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Simon Walker, Ulla-Maria Sahinaho, Sakari Vekki, Mari Sulonen,Jari A. Laukkanen,Sarianna Sipilä,Heikki Peltonen,Eija Laakkonen,Maarit Lehti
European Journal of Applied Physiologyno. 7 (2024): 1-15
BJU INTERNATIONAL (2024)
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