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个人简介
Prof. Dr. Eric Thouvenot is a Physician and the Head of the Department of Neurology at the University Hospital of Nimes. He is also Professor of Neurology and a Researcher at the Functional Genomics Institute (CNRS) and University of Montpellier.
Former President of the Francophone Society of Multiple Sclerosis (SFSEP), he is mainly involved in MS and I lead the MS Clinic in Nîmes University Hospital. He developed a biobank of CSF and serum samples from MS patients since 2005 and participates to several national and international efforts for biobanking (OFSEP, BioMS-eu). He obtained several grants from charities (ARSEP Foundation) and pharmaceutical companies (Novartis, Biogen-Idec, Genzyme, Merck) dedicated to clinical and pathophysiological studies in MS, especially comparing biomarkers of progression in MS using MRI, OCT and biological markers.
He coordinates a French national randomized double-blind RCT aimed at evaluating the clinical efficacy of Vitamin D to reduce conversion to MS after a clinically isolated syndrome in 316 patients. He obtained an ANR (Agence Nationale de la Recherche) grant dedicated to analyse modifications of gene expression in circulating lymphocytes of D-lay MS patients using single-cell RNA sequencing, and develops pharmacogenomics analyses of treatments effects in MS patients.
He is also involved in translational research focused on the discovery of novel biomarkers of MS based on CSF proteomics, and high throughput approaches, as well as high sensitivity analysers to measure serum neurofilament light chains (NfL) and glial acidic fibrillary protein (GFAP) like Ella, platform and single molecule array (Simoa). He developed partnerships with different laboratories to discover and validate new biomarkers of MS.
研究兴趣
论文共 305 篇作者统计合作学者相似作者
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Guillaume Jouvenot, Guilhem Courbon,Mathilde Lefort,Fabien Rollot,Romain Casey,Emmanuelle Le Page,Laure Michel,Gilles Edan,Jérome de Seze,Laurent Kremer,Kevin Bigaut,Sandra Vukusic,
JAMA neurologyno. 5 (2024): 490-498
Strokeno. 8 (2024): 2086-2093
JAMA neurology (2024)
Jason Freeman,Silvia Delgado,Enrique Alvarez,Eric Thouvenot, Annette Okai,Alit Bhatt, Wenjia Wei,Tjalf Ziemssen
Neurologyno. 17_supplement_1 (2024)
Multiple sclerosis (Houndmills, Basingstoke, England)no. 3 (2024): 381-395
Journal of Neurologyno. 7 (2024): 1-9
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