Research Interests
Desmoplastic Tumor Microenvironment

Cellular and signal transduction mechanisms of fibrous desmoplastic activation, maintenance, and function
Pancreatic, lung, renal, and other transformative alterations regulated by cancer-associated fibroblasts (CAFs) and their self-derived extracellular matrices (ECMs)
Clinical implications, translational aspects and means of microenvironment activation assessments; compartmental —tumoral and stromal— biomarker detection using multi-spectral and batch digital imaging analyses
Decoupling of biochemical and biomechanical influences of desmoplasia by combinational 3D models of cell-derived ECMs (known as CDMs) and biomimetic material engineering