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Bio
My long-term research interests involve the development of a comprehensive understanding of key developmental pathways and how those pathways contribute to human disease. My academic training and research experience have provided me with an excellent background in multiple biological disciplines including molecular biology, cellular biology, biochemistry, and genetics. As an undergraduate, I was able to conduct research with Dr. Alessandra Baracca on the functional characterization of mitochondrial ATP synthase activity in lymphocytes isolated from patients affected by NARP disease (Neuropathy, Ataxia and Retinitis Pigmentosa), and I gained expertise in the biochemical characterization of mitochondrial complexes. After graduation in 2006, I joined the Colorectal Cancer study Group of Modena with a grant of the local University. As a predoctoral student with Prof. Maurizio Poz de Leon, my research focused on the mismatch repair genes (MR) sequencing and microsatellite instability. My research was also centred on the seeking of constitutional TP53 and TP73 mutations in patients and families with clinical features of Lynch syndrome, but without involvement of the DNA MR genes. The PhD studentship available through the University of Modena and Reggio Emilia have provided me a good background for developing research project on cancer biology. My doctorate was focused on the Methylation analysis of MLH1 mismatch repair gene in selected patients with Lynch syndrome. During my PhD experience, from 2007 to 2010, I was able to set up a fruitfully collaboration with the Human Genetic Group at Leiden University Medical Center were I improved my technical skills and the ability to develop a project. In Leiden I worked with Dr. Juul Wijnen, and I boosted my skills on molecular and genetic biology, mainly preformed methylation analysis of the MLH1 gene promoter in Lynch syndrome families and PMS2 gene. I started my experience at the Seràgnoli Institute with a grant of the local University (Bologna University), and I began my career in the field of hematological diseases, focusing my research on the identification of new therapeutic targets for Multiple Myeloma. My experience as a postdoctoral started in 2011 at Seràgnoli Institute with the supervision of Prof. Michele Cavo, and it has always focused on translational research in Multiple Myeloma. My sponsor Prof. Michele Cavo is an internationally recognized leader in the Multiple Myeloma field and has an extensive record for training postdoctoral fellows.
Research Interests
Papers共 107 篇Author StatisticsCo-AuthorSimilar Experts
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Nature Communicationsno. 1 (2024): 1-18
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2023): S14-S14
Frontiers in oncology (2023): 1208741
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2023): S243-S244
Clinical and experimental medicineno. 8 (2023): 5227-5239
CLINICAL LYMPHOMA MYELOMA & LEUKEMIA (2023): S72-S72
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Author Statistics
#Papers: 107
#Citation: 586
H-Index: 14
G-Index: 24
Sociability: 6
Diversity: 0
Activity: 1
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