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Bio
I have obtained a master degree in Pharmaceutical Chemistry and Technology from the University of Salerno (Italy) in 2009 by defending a thesis on the effect of Toll- like receptor 9 agonists in modulating immune responses in lung cancer. In 2010 I joined the laboratory of Prof. Cecilia Garlanda and Prof. Alberto Mantovani to study the inflammatory processes associated with cancer development and progression. In 2014, I was awarded a fellowship from the Italian Foundation for Cancer Research (FIRC-AIRC). In 2015 I obtained my PhD in Immunology and Life Sciences from The Open University (Milton Keynes, UK) and Humanitas Clinical and Research Centre. During my doctoral studies, I uncovered the essential role of Pentraxin 3 and the complement system in regulating tumour-promoting inflammation. Moreover, I studied the properties of Interleukin-1 receptor 8 in controlling NK cell activity and I described its role as an NK cell checkpoint receptor in both viral infections and anti-tumour immunity. Notably, these discoveries were recognised by the ACTERIA-EFIS award as the best PhD thesis in Immunology in Europe (2015-2018).
In 2016 I joined the group led by Dr. Santiago Zelenay at the Cancer Research UK Manchester Institute, where I was awarded an EMBO long-term fellowship in 2016 and an EMBO advanced fellowship in 2019 to investigate the mechanisms of immune evasion in cancer driven by cyclooxygenase 2/prostaglandin E2 axis, in a project with extensive translational potential.
After more than 6 years in UK, in 2022, thanks to the AIRC start-up programme, I joined the IRCCS Humanitas Research Hospital to lead the Cellular and Molecular Oncoimmunology (CMO) Lab. My group focuses on understanding the instructive mechanisms of immune escape in cancer with the aim of designing new therapeutic strategies for patients.
Research Interests
Papers共 50 篇Author StatisticsCo-AuthorSimilar Experts
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Silvia Carnevale,Andrea Ponzetta,Anna Rigatelli,Roberta Carriero,Simone Puccio,Domenico Supino, Giovanna Grieco, Piera Molisso,Irene Di Ceglie,Francesco Scavello,Chiara Perucchini,Fabio Pasqualini,
crossref(2024)
Silvia Carnevale,Andrea Ponzetta,Anna Rigatelli,Roberta Carriero,Simone Puccio,Domenico Supino, Giovanna Grieco, Piera Molisso,Irene Di Ceglie,Francesco Scavello,Chiara Perucchini,Fabio Pasqualini,
crossref(2024)
Silvia Carnevale,Andrea Ponzetta,Anna Rigatelli,Roberta Carriero,Simone Puccio,Domenico Supino, Giovanna Grieco, Piera Molisso,Irene Di Ceglie,Francesco Scavello,Chiara Perucchini,Fabio Pasqualini,
crossref(2024)
Silvia Carnevale,Andrea Ponzetta,Anna Rigatelli,Roberta Carriero,Simone Puccio,Domenico Supino, Giovanna Grieco, Piera Molisso,Irene Di Ceglie,Francesco Scavello,Chiara Perucchini,Fabio Pasqualini,
crossref(2024)
Silvia Carnevale,Andrea Ponzetta,Anna Rigatelli,Roberta Carriero,Simone Puccio,Domenico Supino, Giovanna Grieco, Piera Molisso,Irene Di Ceglie,Francesco Scavello,Chiara Perucchini,Fabio Pasqualini,
CANCER IMMUNOLOGY RESEARCHno. 4 (2024): 413-426
crossref(2024)
Silvia Carnevale,Andrea Ponzetta,Anna Rigatelli,Roberta Carriero,Simone Puccio,Domenico Supino, Giovanna Grieco, Piera Molisso,Irene Di Ceglie,Francesco Scavello,Chiara Perucchini,Fabio Pasqualini,
crossref(2024)
Aurora Gazzillo, Camilla Volponi,Cristiana Soldani,Michela Anna Polidoro,Barbara Franceschini, Ana Lleo,Eduardo Bonavita, Matteo Donadon
Silvia Carnevale,Andrea Ponzetta,Anna Rigatelli,Roberta Carriero,Simone Puccio,Domenico Supino, Giovanna Grieco, Piera Molisso,Irene Di Ceglie,Francesco Scavello,Chiara Perucchini,Fabio Pasqualini,
crossref(2024)
Charles H. Earnshaw,Shih-Chieh Chiang,Agrin Moeini, Maria Koufaki,Eduardo Bonavita, Laetitia Nebot-Bral, Massimo Russo,Charlotte Bell, Theophile Bigirumurame,Jérémie Nsengimana,Julia Newton-Bishop, Christopher E. Griffiths,
Cancer Researchno. 6_Supplement (2024): 2647-2647
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