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Bio
His research has focused upon multiple aspects of phospholipid biochemistry, molecular biology and genetics. A significant portion of his career has been dedicated to elucidating the mechanisms of inter-organelle phospholipid traffic and metabolism, using yeast genetics and molecular biology. Additional studies have focused upon elucidating the structural details of phospholipid-protein interactions, especially with the phospholipid constituents of pulmonary surfactant. Current topics being pursued in his laboratory include: 1) antagonism of innate immunity and respiratory viral infections by anionic phospholipids present in pulmonary surfactant, 2) application of lipids as inhibitors of viral infection and virus- induced exacerbations of chronic lung diseases, 3) development of high throughput screening strategies to target lipid metabolism in pathogens (bacteria, fungi and parasites) and neoplastic tissues for therapeutic purposes.
Research Interests
Papers共 254 篇Author StatisticsCo-AuthorSimilar Experts
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Rüdiger Groß, Hanna Reßin,Pascal von Maltitz,Dan Albers, Laura Schneider, Hanna Bley,Markus Hoffmann,Mirko Cortese,Dhanu Gupta,Miriam Deniz,Jae-Yeon Choi,Jenny Jansen,
Nature Microbiologyno. 4 (2024): 1-17
Immunological reviewsno. 1 (2024): 166-186
Journal of biological chemistry/The Journal of biological chemistryno. 3 (2023): 103685-103685
Journal of biological chemistry/The Journal of biological chemistryno. 5 (2023): 104659-104659
Virusesno. 3 (2023): 747
Alicia Rizzo,Sarah Haeger,Alison Wallbank,Yimu Yang,Kaori Oshima, Christophe Langouet Astrie,James Colbert,Katrina Kopf,Dennis Voelker,Julie Bastarache,Lynda McCaig
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Author Statistics
#Papers: 250
#Citation: 19548
H-Index: 65
G-Index: 138
Sociability: 7
Diversity: 3
Activity: 17
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