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Bio
The translational research of Douglas L. Packer, M.D., focuses on the mechanisms and ablation of atrial fibrillation and other cardiac arrhythmias, and the development of external beam carbon and proton particle catheter-free ablation of arrhythmias.
Focus areas:
Atrial fibrillation. Whether percutaneous catheter ablation also has a favorable effect on survival, stroke, quality of life, and healthcare costs has not been studied extensively, but is being studied by Dr. Packer as Principal Investigator of the CABANA Trial.
Ventricular tachycardia. Dr. Packer is working to develop new means of treating ventricular tachycardia. Dr. Packer codeveloped a needle electrode catheter, which allows for the extension of a heated saline via needle tip into the tissue to create larger lesions.
The Catheter Ablation versus Antiarrhythmic Drug Therapy for Atrial Fibrillation (CABANA) Trial. A multicenter randomized trial compares the effect of percutaneous catheter ablation versus current state-of-the-art drug therapy on total mortality, disabling stroke, serious bleeding or cardiac arrest as the primary endpoint. The CABANA Trial will look at total mortality as the key secondary endpoint along with quality of life and healthcare costs.
Biophysics of ablation using special catheters for ventricular arrhythmias. Dr. Packer is investigating the source of stroke event occurrence during radiofrequency ablation with irrigation tip, laser, or cryo and other catheters.
External photon beam and carbon beam radiation. Dr. Packer's present research seeks to investigate whether external photon beam and carbon beam radiation can be used to successfully target arrhythmogenic cardiac tissue and produce sustained, as well as controllable. He holds a major patent/intellectual property for this scientific work.
Research Interests
Papers共 495 篇Author StatisticsCo-AuthorSimilar Experts
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Lucas V. Boersma, Andrea Natale,David E. Haines,David B. De Lurgio,Nitesh Sood,Francis E. Marchlinski,Hugh Calkins,Robert H. Hoyt, Prashanthan Sanders, James Irwin,Douglas L. Packer, Suneet Mittal,
Heart Rhythmno. 5 (2024): S114-S115
Lucas V. Boersma, Andrea Natale,David E. Haines,David B. De Lurgio,Nitesh Sood,Francis E. Marchlinski,Hugh Calkins,Robert H. Hoyt, Prashanthan Sanders, James Irwin,Douglas L. Packer, Suneet Mittal,
Heart Rhythmno. 5 (2024): S351
Douglas L. Packer,Heidi May, Heather Maestas, T. Jared Bunch,Brian G. Crandall,Jeanne E. Poole,Michael J. Cutler
Heart Rhythmno. 5 (2024): S128
Circulation. Arrhythmia and electrophysiologypp.e012697-e012697, (2024)
Riccardo Cappato,Daniel B Mark,Adam P Silverstein,Peter A Noseworthy,Gianluca Bonitta,Jeanne E Poole,Jonathan P Piccini,Tristram D Bahnson,Melanie R Daniels, Hussein R Al-Khalidi,Kerry L Lee,Douglas L Packer,
Viet Le,Heidi May,Tami L. Bair,Stacey Knight,Benjamin D. Horne,Michael J. Cutler,Douglas L. Packer,Kirk U. Knowlton, Jeffrey L. Anderson
Heart Rhythmno. 5 (2024): S165-S166
Heart Rhythm (2024)
Douglas L. Packer, Heather Maestas,Daniel B. Mark,Jeanne E. Poole,Tristram D. Bahnson,Kerry L. Lee, Heidi May
Heart Rhythmno. 5 (2024): S234
Tatsuhiko Hirao,Maryam Rettmann, Masayoshi Suda,Amanda J. Deisher, Taro Koya,Atsushi Suzuki,Kimitake Imamura, Katie Newman,Jon Kruse, Dean Shumway,Kenneth Merrell,Douglas L. Packer,
Heart Rhythmno. 5 (2024): S175
World journal of cardiologyno. 2 (2023): 64-75
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