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Staphylococcus aureus is the leading cause of bacterial infections in developed countries and Methicillin-Resistant S. aureus (MRSA) is one of the most significant antibiotic resistant bacteria world-wide. For this reason, my research is dedicated to unravel the molecular mechanisms underlying the ability of Staphylococcus aureus to cause disease and to develop antibiotic resistance. Focus has been on the highly conserved ClpP proteases and Clp chaperones that we have shown to be absolutely essential for the virulence of Staphylococcus aureus. We are currently investigating how the Clp proteases and chaperones central activities such as:
Virulence gene regulation
Antibiotic resistance
Cell division
The long-term objective of my research is to provide the scientific basis for the development of drugs interfering with these mechanisms.
Virulence gene regulation
Antibiotic resistance
Cell division
The long-term objective of my research is to provide the scientific basis for the development of drugs interfering with these mechanisms.
研究兴趣
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LETTERS IN APPLIED MICROBIOLOGYno. 2 (2024)
Camilla Henriksen,Kristoffer T. Baek,Katarzyna Wacnik,Clement Gallay,Jan-Willem Veening,Simon J. Foster,Dorte Frees
MOLECULAR MICROBIOLOGYno. 1 (2024): 98-115
Tobias Krogh Nielsen, Ida Birkjær Petersen,Lijuan Xu, Maria Disen Barbuti, Viktor Mebus, Anni Justh,Abdulelah Ahmed Alqarzaee,Nicolas Jacques,Cécile Oury,Vinai Thomas,Morten Kjos, Camilla Henriksen,
Antimicrobial agents and chemotherapypp.e0033524-e0033524, (2024)
Lijuan Xu, Carsten Henriksen, Viktor Hundtofte Mebus,Romain Guérillot,Andreas Petersen,Nicolas Jacques,Jhih-Hang Jiang,Rico Derks,Elena Sánchez-López,Martin Giera,Kirsten Leeten,Timothy P. Stinear,
Antimicrobial Agents and Chemotherapyno. 6 (2023)
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Lijuan Xu, Camilla Henriksen, Viktor Hundtofte Mebus,Romain Guérillot,Andreas Petersen,Nicolas Jacques,Jhih-Hang Jiang,Rico Derks,Elena Sánchez-López,Martin Giera,Kirsten Leeten,Timothy P Stinear,
biorxiv(2023)
Helene M S Eld,Emilie M Nielsen,Peter R Johnsen,Mauro Marengo, Ida W Kamper, Lise Frederiksen,Francesco Bonomi,Dorte Frees,Stefania Iametti,Hanne Frøkiær
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