基本信息
浏览量:2
职业迁徙
个人简介
Research Interests
Cells assemble a spectrum of interdependent F-actin networks that, together, move cells and organelles, establish polarity, confer mechanical properties and organize cells in tissues. Our research investigates the mechanisms by which cellular actin filaments assemble types of distinct networks that function in a coordinated manner. Two well-characterized actin networks are: 1) sheet-like, dendritic networks that power propulsive events as cells extend membrane and migrate and 2) contractile actomyosin networks that generate tension and pulling forces. Dendritic actin networks and actomyosin networks are often situated in close proximity in cells, yet, how these two very different networks form and function in a coordinated manner to maintain a dynamic, but coherent, global cytoskeleton is unknown.
Cells assemble a spectrum of interdependent F-actin networks that, together, move cells and organelles, establish polarity, confer mechanical properties and organize cells in tissues. Our research investigates the mechanisms by which cellular actin filaments assemble types of distinct networks that function in a coordinated manner. Two well-characterized actin networks are: 1) sheet-like, dendritic networks that power propulsive events as cells extend membrane and migrate and 2) contractile actomyosin networks that generate tension and pulling forces. Dendritic actin networks and actomyosin networks are often situated in close proximity in cells, yet, how these two very different networks form and function in a coordinated manner to maintain a dynamic, but coherent, global cytoskeleton is unknown.
研究兴趣
论文共 128 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Phillip S Gross,Violeta Duran Laforet,Zeeba Manavi,Sameera Zia, Sung Hyun Lee, Nataliia Shults,Sean Selva,Enrique Alvarez,Jason R Plemel,Dorothy P Schafer,Jeffrey K Huang
bioRxiv : the preprint server for biology (2024)
ANNALS OF THE NEW YORK ACADEMY OF SCIENCESno. 1 (2024): 38-50
Travis E. Faust, Yi-Han Lee, Ciara D. O’Connor, Margaret A. Boyle,Georgia Gunner,Ana Badimon,Pinar Ayata,Anne Schaefer,Dorothy P. Schafer
bioRxiv the preprint server for biology (2024)
CELL REPORTS MEDICINEno. 4 (2024)
Artem Arutyunov,Violeta Durán-Laforet,Shenjian Ai, Loris Ferrari, Robert Murphy,Dorothy P Schafer,Robyn S Klein
Biomoleculesno. 7 (2024)
Immunityno. 5 (2023): 914-925
biorxiv(2023)
Salome Funes,Del Hayden Gadd, Michelle Mosqueda,Jianjun Zhong,Jonathan Jung, Shankaracharya, Matthew Unger, Debra Cameron,Pepper Dawes,Pamela J. Keagle,Justin A. McDonough,Sivakumar Boopathy,
Journal of Visualized Experiments (2023)
Cell Reportsno. 9 (2023): 113031-113031
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn