基本信息
浏览量:196
职业迁徙
个人简介
Del Vecchio’s group focuses on model-based analysis, design, and control of biomolecular circuits in living cells. The objective of the research is to make genetic circuits more modular, robust to context, and hence make design more scalable. At the same time, we are investigating circuit design approaches that will enable accurate and precise in vivo control of gene expression. One of our target applications is the design of synthetic genetic circuits that accurately control cell fate-determining transcription factor levels, for reprogramming cell fate. Our approach is grounded on rigorous mathematical analysis of physics-based models of biological network dynamics, on the development of new control-theoretic tools for design, and on theory-educated experiments in living cells, from bacterial to mammalian.
研究兴趣
论文共 257 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
Huifeng Du,Simone Bruno,Kalon J. Overholt,Sebastian Palacios,Hsin-Ho Huang,Carlos Barajas, Ben Gross, Cindy Lee, Haley K. Evile,Nuno Rufino de Sousa,Antonio Gigliotti Rothfuchs,Domitilla Del Vecchio
Biosensors and Bioelectronics: Xpp.100488, (2024)
npj Systems Biology and Applicationsno. 1 (2024): 1-10
Sebastian Palacios,Simone Bruno, Ron Weiss, Elia Salibi, Andrew Kane,Katherine Ilia,Domitilla Del Vecchio
biorxiv(2024)
arXiv (Cornell University) (2023)
引用0浏览0引用
0
0
2023 62ND IEEE CONFERENCE ON DECISION AND CONTROL, CDCpp.2712-2718, (2023)
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn