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个人简介
Dmitriy Ovcharenko is a cell and molecular biologist by training, holding degrees in biology, chemistry, ecology, and pharmacology, expert in RNA interference (RNAi) and preclinical research. Dr.Ovcharenko main research interest is therapeutic application of RNA interference (RNAi) technology - siRNA and microRNA therapeutics. microRNAs are small RNA molecules encoded in the genomes of plants and animals that regulate the expression of genes by binding to the 3'-untranslated regions of specific mRNAs. microRNA is involved in the RNA interference (RNAi) mechanism and play a critical role in gene silencing. Misregulation of miRNA expression was found in several diseases including cancer. Application of microRNAs as therapeutic targets represent a novel molecular based approach for developing new medicines for many incurable diseases, including cancer.
Dmitriy Ovcharenko worked as research scientist at following organizations: Lawrence Berkeley National Laboratory (Edward M. Rubin Laboratory), Ambion (David Brown Laboratory, now Mirna Therapeutics), Asuragen (Matt Winkler), and Terapio (Curt Bilby). Dmitriy also worked as a consultant at Sante Ventures and ATMI (now Entegris).
Dmitriy performed undergraduate and graduate studies at Novosibirsk State University (1996-2000, 2000-2002) and conducted his doctoral work at University of Texas at Austin (2004-2008).
Dmitriy Ovcharenko is a founder and CEO of Altogen Labs (since 2009), a GLP-compliant contract research organization (CRO) in Austin,Texas providing a wide range of preclinical laboratory research services and pharmacology/toxicology studies to pharma and biotechnology industry (Global Health & Pharma publications about Altogen Labs: Medical Discovery and Innovation / Preclinical Contract Research Studies). Scientists at Altogen Labs perform gene silencing (RNAi) and xenograft preclinical studies in collaboration with cancer research centers. Altogen Labs bioremediation products (oil-degrading bacteria) and services are used for environmental remediation by oil and gas industry worldwide.
Dmitriy Ovcharenko is also a founder of Altogen Chemicals, a manufacturer and worldwide distributor of biochemicals, organic and inorganic chemicals, including ultra-pure hexachlorodisilane (HCDS) used in several high tech industries including semiconductor and solar energy.
Dr. Ovcharenko is a member of the following professional organizations: American Association for Cancer Research, American Society for Pharmacology & Experimental Therapeutics, American Society for Cell Biology, and affiliated with following research journals: Cancer Research Journal, Nucleic Acid Research, and Gene Therapy Journal.
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