基本信息
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Career Trajectory
Bio
Dr. Gibbons maintains a large and active research laboratory focused on understanding the regulation of cancer cell invasion and metastasis by intrinsic tumor cell factors and the role of the tumor microenvironment (immune cells and extracellular matrix) in those same processes. The team has specific expertise in understanding KRAS mutant lung cancer. In their studies the team uses human samples and clinical data, cell line models and mouse models. Recently, Dr. Gibbons demonstrated that for cancer cells to escape the primary lung tumor and colonize new organs, they need to suppress the immune system, a process that is mediated in part by suppression and exhaustion of T cell activity, which is coordinated in part by the protein PD-L1. Dr. Gibbons’ translational research suggests that immunotherapy may have anti-metastatic effects and has driven the development of new clinical trials, particularly in the area of acquired resistance to immunotherapy.
Research Interests
Papers共 469 篇Author StatisticsCo-AuthorSimilar Experts
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期刊级别
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Haniel A Araujo, Ximo Pechuan-Jorge,Teng Zhou,Minh Truong Do, Xin Hu,Frank R Rojas Alvarez, Maria E Salvatierra, Heladio P Ibarguen, Richard Lee, Rashi Raghulan, Harshit Shah, Mariela A Moreno Ayala,
Cancer discovery (2024)
Cancer Researchno. 6_Supplement (2024): 3379-3379
Muhammad Aminu, Bo Zhu,Natalie Vokes,Hong Chen,Lingzhi Hong,Jianrong Li,Junya Fujimoto, Yuqui Yang, Tao Wang,Bo Wang,Alissa Poteete,Monique B Nilsson,
Research square (2024)
Cancer Researchno. 6_Supplement (2024): 1940-1940
Kang Qin,Kaiwen Wang,Shenduo Li,Lingzhi Hong, Priyadharshini Padmakumar,Rinsurongkawong Waree,Shawna M. Hubert,Xiuning Le,Natalie Vokes,Kunal Rai,Ara Vaporciyan,Don L. Gibbons,
Cancersno. 5 (2024): 935
Nature Communicationsno. 1 (2024): 3152-3152
Sang T Kim,Yanshuo Chu,Mercy Misoi,Maria E Suarez-Almazor,Jean H Tayar,Huifang Lu,Maryam Buni, Jordan Kramer,Emma Rodriguez, Zulekha Hussain,Sattva S Neelapu,Jennifer Wang,
ESMO Open (2024)
Cancer Researchno. 6_Supplement (2024): 1502-1502
Research square (2024)
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Author Statistics
#Papers: 471
#Citation: 14942
H-Index: 65
G-Index: 119
Sociability: 8
Diversity: 3
Activity: 421
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