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Bio
Dr. Ray has over 15 years of research experience in the field of cancer cell signaling with specific emphasis on understanding the role of post-translational protein modifications during oncogenesis. His research goal involves in identifying ubiquitination machineries involved in the maintenance of oncoproteins’ stabilities including epidermal growth factor receptor (EGFR) and mutant KRAS. He seeks to then further translate such findings to develop novel and efficacious anticancer strategies.
Dr. Ray also has a research interest in understanding the roles of Tumor Necrosis Factor (TNF-α) in radiation pneumonitis and using that to develop a strategy of lung radioprotection. In addition, he has several intra-institutional collaborative projects including one with Dr. David Beer in the Department of Surgery, whose laboratory is studying the novel role of RNF128/Grail, a RING-family ubiquitin ligase (E3) in mutant TP53 protein stability during Barrett’s progression. Another recent collaboration is with Dr. Nithya Ramnath from the Department of Internal Medicine. Her lab is exploring the roles of Vitamin D in metabolizing Cytochrome P450 (CYP24A1), nuclear division, and mitochondrial biogenesis which is critical for lung tumor growth and invasion.
Dr. Ray also has a research interest in understanding the roles of Tumor Necrosis Factor (TNF-α) in radiation pneumonitis and using that to develop a strategy of lung radioprotection. In addition, he has several intra-institutional collaborative projects including one with Dr. David Beer in the Department of Surgery, whose laboratory is studying the novel role of RNF128/Grail, a RING-family ubiquitin ligase (E3) in mutant TP53 protein stability during Barrett’s progression. Another recent collaboration is with Dr. Nithya Ramnath from the Department of Internal Medicine. Her lab is exploring the roles of Vitamin D in metabolizing Cytochrome P450 (CYP24A1), nuclear division, and mitochondrial biogenesis which is critical for lung tumor growth and invasion.
Research Interests
Papers共 70 篇Author StatisticsCo-AuthorSimilar Experts
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Dyke P McEwen,Paramita Ray,Derek J Nancarrow,Zhuwen Wang, Srimathi Kasturirangan, Saeed Abdullah, Ayushi Balan, Rishi Hoskeri,Dafydd Thomas,Theodore S Lawrence,David G Beer,Kiran H Lagisetty,
JCI insightno. 13 (2024)
Paramita Ray,Sangeeta Jaiswal,Daysha Ferrer-Torres,Zhuwen Wang,Derek Nancarrow, Meghan Curtin, May San Martinho, Shannon M Lacy, Srimathi Kasturirangan,Dafydd Thomas,Jason R Spence, Matthias C Truttmann,
Molecular cancer research : MCR (2024)
Srimathi Kasturirangan,Derek J. Nancarrow, Ayush Shah,Kiran H. Lagisetty,Theodore S. Lawrence,David G. Beer,Dipankar Ray
Cell Death & Diseaseno. 3 (2024): 1-12
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bioRxiv (Cold Spring Harbor Laboratory) (2023)
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