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He proved that retinaldehyde was contained in a protein of the so-called "purple membrane" of Halobacterium. This protein was isolated and called bacteriorhodopsin. After returned to Germany, Oesterhelt showed that physiological function of bacteriorhodopsin is to pump protons out of the cell. Members of his department at the Max Planck Institute for Biochemistry researched the structure-function relationships of membrane proteins and other microbial rhodopsins such as halorhodopsin, which later became a molecular tool in optogenetics. In 2021 he received the Albert Lasker Award for Basic Medical Research.
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论文共 383 篇作者统计合作学者相似作者
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Wilhelm Maximilian Hützler,Estelle Mossou, Ronald Vollrath,Miriam Kohagen, Imadine El Ghrissi,Martin Grininger,Giuseppe Zaccai,Jens Smiatek,Dieter Oesterhelt
GENESno. 3 (2019): 194
Karthik Shivaji Paithankar, Mathias Enderle, David C Wirthensohn,Arthur Miller,Matthias Schlesner, Friedhelm Pfeiffer,Alexander Rittner, Martin Grininger,Dieter Oesterhelt
Genesno. 10 (2018): 493
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