The primary research focus of Dennis W. Dickson, M.D., is the neuropathologic characterization of brains from prospective and longitudinal research studies sponsored by the National Institute on Aging. Brains come from the Mayo Clinic Alzheimer's Disease Research Center (NIA P50 AG16574), the Mayo Clinic Study of Aging (NIA U01 AG06786), and the Einstein Aging Study at Albert Einstein College of Medicine (NIA P01 AG03949). These studies, which differ in patient characteristics, include elderly community volunteers and recruits from population-based sampling. Fixed and frozen brain samples are obtained at autopsy and used for diagnostic evaluations and research with neurohistology, immunohistochemistry, electron microscopy and image analysis, and immunoassays. Dr. Dickson is part of a team of internationally recognized researchers and clinicians with specialty training in Parkinson's disease and movement disorders supported by the American Parkinson Disease Association.