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职业迁徙
个人简介
Our laboratory has 3 primary research goals. The FIRST goal is to understand how glioblastoma (GBM) cell indoleamine 2,3 dioxygenase 1 (IDO; IDO1) increases immunosuppressive T-reg infiltration, suppresses the immune response, and decreases overall survival in mouse models and human subjects with glioblastoma. Our previous work discovered that glioblastoma cell IDO1 non-enzymically upregulates immunosuppressive complement factor H (CFH) and factor H-like 1 (FHL-1) in human GBM cells, which in-turn, suppresses the anti-tumor immune response through intratumoral T-reg and MDSC accumulation.
研究兴趣
论文共 190 篇作者统计合作学者相似作者
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Brain, Behavior, & Immunity - Health (2024): 100753-100753
Siqi Chen,Jie Fan,Ping Xie,Jihae Ahn, Michelle Fernandez,Leah K Billingham,Jason Miska, Jennifer D Wu,Derek A Wainwright,Deyu Fang, Jeffrey A Sosman,Yong Wan,
The Journal of clinical investigation (2024)
Amna Siddiqui, Dylan Ross, Ronak Jani,Vikram Prabhu,Shelly Lo,Derek Wainwright,Stasia Rouse,Jigisha Thakkar
Akriti Shrestha, Mikaela Kasperek, Maria Elisa Caetano-Silva,Derek Wainwright, Robert McCuscker,Jacob Allen
Neuro-oncologyno. Supplement_5 (2023): v147-v148
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Amna Siddiqui, Dylan Ross, Ronak H Jani,Vikram C Prabhu,Shelly Lo,Derek A Wainwright,Stasia Rouse, Tamer Refaat, Yirong Zhu,Jigisha P Thakkar
crossref(2023)
Alan L. Chang,Jason Miska,Derek A. Wainwright,Mahua Dey, Claudia V. Rivetta,Dou Yu,Deepak Kanojia,Katarzyna C. Pituch,Jian Qiao,Peter Pytel, Yu Han,Meijing Wu,
crossref(2023)
Peiwen Chen,Fatima Khan, Yiyu Lin, Heba Ali,Lizhi Pang,Madeline Dunterman,Wen-Hao Hsu,Katie Frenis,R Grant Rowe,Derek Wainwright,Kathleen McCortney, Leah Billingham,
Research square (2023)
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Amna R. Siddiqui, Dylan D. Ross, Ronak Jani,Vikram C. Prabhu,Shelly S. Lo,Derek A. Wainwright,Stasia Rouse,Tamer Refaat,Yuanchang Zhu,Jigisha P. Thakkar
Neuro-oncologyno. Supplement_5 (2023): v211-v211
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