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个人简介
The Dougherty group in the Division of Chemistry and Chemical Engineering at the California Institute of Technology conducts research in organic chemistry and chemical biology. The major focus of the group seeks a chemical-scale understanding of ion channels and neuroreceptors. These integral membrane proteins are the molecules of memory, learning, and sensory perception. They are also the targets of pharmaceuticals intended to treat Alzheimers disease, Parkinsons disease, schizophrenia, learning and attention deficits, and many others disorders. By using a combination of organic synthesis, molecular biology, electrophysiology, and computer modeling, detailed structural and mechanistic insights into these complex systems can be obtained.
研究兴趣
论文共 443 篇作者统计合作学者相似作者
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Molecular pharmacologyno. 6 (2023): 339-347
bioRxiv (Cold Spring Harbor Laboratory) (2023)
ENEUROno. 5 (2023): ENEURO.0449-22.2023
MOLECULAR PHARMACOLOGYno. 6 (2023): 339-347
ACS Chemical Neuroscienceno. 15 (2022): 2338-2345
Zoe G Beatty,Anand K Muthusamy, Elizabeth K Unger,Dennis A Dougherty, Lin Tian,Loren L Looger, Amol V Shivange,Kallol Bera, Henry A Lester,Aaron L Nichols
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