基本信息
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职业迁徙
个人简介
Research Interests
My laboratory has been a leader in characterization of structure and function of molecules of blood plasma, platelets, and extracellular matrix. We are best known for studies of fibronectin, thrombospondins, and vitronectin and participate in collaborative studies that utilize the reagents and expertise that we have developed over the years..
For the past two decades, we have worked closely with colleagues in Allergy and Pulmonary and Critical Care Medicine to study activation and trafficking of eosinophils in asthma. Current asthma-related projects include characterizing the proteomes and phosphoproteomes of resting and activated eosinophils (in collaboration with the Josh Coon laboratory); describing the molecular anatomy of and signaling behind the radical changes in eosinophils that occur upon activation with cytokines, chemokines, and other mediators; exploring effects of interactions with periostin, an extracellular matrix protein deposited in the asthmatic lung, on behavior of eosinophils; and identification of biomarkers that differentiate among different types and stages of asthma. In addition, we study adhesion to extracellular matrix proteins of bacteria that are respiratory pathogens or commensal to the bronchial tree.
研究兴趣
论文共 488 篇作者统计合作学者相似作者
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Andrea Resovi,Perla Persichitti,Laura Brunelli,Lucia Minoli,Patrizia Borsotti, Giulia Garattini,Matteo Tironi,Erica Dugnani, Miriam Redegalli,Giulia De Simone,Roberta Pastorelli,Maria Rosa Bani,
Connective Tissue Diseasepp.455-473, (2021)
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#Papers: 490
#Citation: 30539
H-Index: 95
G-Index: 153
Sociability: 7
Diversity: 4
Activity: 16
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