基本信息
views: 19
![](https://originalfileserver.aminer.cn/sys/aminer/icon/show-trajectory.png)
Bio
- Principal Investigator in CECAD, University of Cologne, Germany. Proteostasis of aging and stem cells.
- Postdoctoral fellow in Dr. Andrew Dillin’s lab at the Salk Institute (La Jolla, USA) and the Li Ka Shing Center, University of California (Berkeley, USA). Proteostasis of aging and stem cells
- PhD from Dr. Joan Guinovart’s lab, Metabolic Engineering and Diabetes Therapy Laboratory, Institute for Research in Biomedicine (IRB), Barcelona, Spain. Lafora disease and glycogen metabolism in neurons
Dr. Vilchez seeks to understand how protein homeostasis, or proteostasis, impinges upon stem cell function and aging. His work has shown that increased somatic proteasome activity resulted in increased longevity in the worms. Ectopic expression of the 19S proteosome subunit, rpn-6, is sufficient to extend life span and confer proteotoxic stress resistance. Furthermore, his work has also shown that just like genome stability is essential for the survival of stem cells, proteome stability may have equally important role in stem cell identity and function. In his own lab, Dr. Vilchez would like to continue on his work on proteostasis of aging and stem cells.
Dr. Vilchez has received the Josep Trueta prize for the best research for his PhD work published in Nature Neuroscience in 2007 “Mechanism suppressing glycogen synthesis and its demise in progressive myoclonus epilepsy”, and the Young Scientist award from the Spanish Society of Biochemistry and Molecular Biology.
Research Interests
Papers共 68 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
biorxiv(2024)
NATUREno. 8001 (2024): E20-E20
Natureno. 8001 (2024): E20-E20
bioRxiv (Cold Spring Harbor Laboratory) (2023)
FRONTIERS IN IMMUNOLOGY (2023): 1303072-1303072
Nature agingno. 11 (2023): 1345-1357
Life Science Allianceno. 11 (2023): e202302018-e202302018
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn