基本信息
浏览量:1
职业迁徙
个人简介
Dr. Williams’ laboratory focuses on the cell biology of photoreceptor and RPE cells. His group is especially interested in cell biological studies of the retina in relation to retinal function and inherited retinal disease. Basic science investigations in the laboratory include identifying how proteins and organelles are transported and targeted within the photoreceptor and RPE cells. The identification of roles of different motor proteins has advanced the molecular understanding of cellular events, such as disk membrane renewal and associated retinal disease. The laboratory is also interested in the translation of basic science of the retina to clinical research. Basic studies on myosin VIIa, an unconventional actin-based motor protein, have enabled the establishment of assays for use in preclinical studies on gene therapy for a type of Usher syndrome, an inherited eye disorder that involves both deafness and retinal degeneration. Studies with mutant mice have also led to the development of useful models for retinal degeneration, including age-related macular degeneration.
研究兴趣
论文共 213 篇作者统计合作学者相似作者
按年份排序按引用量排序主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
W Blake Gilmore,Nan W Hultgren,Abhishek Chadha, Sonia B Barocio, Joyce Zhang,Oksana Kutsyr,Miguel Flores-Bellver,M Valeria Canto-Soler,David S Williams
Vision research (2023): 108311-108311
JOURNAL OF NEUROSCIENCEno. 30 (2023): 5468-5482
引用0浏览0WOS引用
0
0
Kapil Bharti, Anneke I. den Hollander,Aparna Lakkaraju, Debasish Sinha,David S. Williams, Silvia C. Finnemann,Catherine Bowes-Rickman, Goldis Malek,Patricia A. D'Amore
加载更多
作者统计
合作学者
合作机构
D-Core
- 合作者
- 学生
- 导师
数据免责声明
页面数据均来自互联网公开来源、合作出版商和通过AI技术自动分析结果,我们不对页面数据的有效性、准确性、正确性、可靠性、完整性和及时性做出任何承诺和保证。若有疑问,可以通过电子邮件方式联系我们:report@aminer.cn