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David Moore, BSc, PhD, DSc, FLS, retired from the Faculty of Life Sciences of the University of Manchester in 2009 after 43 years’ service to the University. Born in Liverpool (1st March 1942) he lived in south Manchester from 1966. Today, he lives in Stockport with his wife, Elizabeth; with daughters Becky (with husband Barney and children Sam and Emily) in Poynton; Sophie (with husband Richard and twins Freya and Chloe) in Timperley. Youngest daughter Amy lives with husband Ross, and son Finn and daughter Etta, in Warwick.
David’s first degree was a 1st Class Joint Honours in Botany and Zoology at the University of Hull in 1963. PhD topic dealt with mutant isolation and linkage mapping in the ink-cap mushroom then called Coprinus cinereus (since renamed Coprinopsis cinerea) and part of his research was carried out in the John Innes Institute (then at Bayfordbury in Hertfordshire).
David moved to an Assistant Lectureship in Genetics at the UoM in 1966. Deciding to study the biochemical genetics of carbohydrate metabolism, starting by isolating mutants of C. cinerea which were resistant to growth inhibition by chemical analogues of glucose and fructose. Subsequent research on these covered aspects as diverse as:
* morphological changes caused by paramorphogens,
* kinetic analysis of sugar transport,
* when most of the mutants turned out to be alleles of a single gene, fine structure gene-mapping
* theoretical considerations of recombination mechanisms.
His research emphasises the experimental study of the developmental biology of mushrooms including genetical, biochemical, physiological and microscopical (including ultra-structural), and molecular analyses of how tissues are constructed and assembled in fungi.
In the early years of the 21st century David headed the British Mycological Society’s (BMS) reaction to the decline in teaching of its science (and, incidentally, the absence of any mention of fungi in the UK National Curriculum for schools) by engaging with the public directly to advance awareness of the role of fungi in everyday life. The BMS Roadshow was developed as a mobile display that travelled around the country to promote mycology to the public. David’s team took care to ensure that the content of the Roadshow addressed the entire span of human existence, from breakfast to supper; from food to pharmaceutical; from habitat to household. By showing how much we all depend on fungi, the BMS Roadshow made clear the links between science, its practical application, and its relevance to daily life.
The Roadshow contributed to National Science Week, several Excellence in Cities programmes, and Science Fairs and Festivals. The backbone of the calendar was the Royal Horticultural Society’s Flower Show programme. The BMS contributed displays to the RHS Chelsea Flower Show for several years, but also appeared at the Tatton Park Flower Show in July, the Malvern Spring Gardening Show in May, and Malvern Autumn Garden and Country Show in September. In July 2004 (the first time it was submitted for judging) the BMS Roadshow was awarded a Silver-Gilt Lindley Medal at the RHS Tatton Park Flower Show, and success continued with a Gold Medal at the Malvern Autumn Garden and Country Show in 2004, a Silver-Gilt at the Malvern Spring Gardening Show 2005, Gold at both Tatton Park 2005 and the Malvern Autumn Show 2005, and Silver at the Chelsea Flower Show 2006. In April 2017, David and his wife Elizabeth were jointly awarded the BMS Award for Outstanding Contribution to Education and Public Outreach.
David also has interests in gravitational biology which arose early in the afternoon of 26 June 1989 with a telephone call from Dr Greg Briarty of the University of Nottingham asking if he was interested in suggesting mycological projects for inclusion in the Juno space mission. At the time, he had already developed interests in mushroom (especially Coprinus) developmental biology but had not thought very seriously about the part that gravity might play in cell biology or development. The phone call spurred that interest, and he was able to assemble a proposal.
Lack of funding resulted in Juno science projects staying on the ground, but along the way, David became a member of the European Space Agency’s Life Science Working Group and he was commissioned to edit the report of this group for publication [Moore, Bie & Oser, H. (1996): Biological and Medical Research in Space; An Overview of Life Sciences Research in Microgravity. Springer-Verlag: Berlin, (569 pp.) republished in softcover format in 2012].
Experimental research established where morphogenetic pattern-forming signals originated, their nature, translocation routes, targets and pattern-forming response pathways. It included 3-D computer graphics for visualisation of hyphal branching patterns and hyphal interactions in microscope images and mathematical models to create startlingly life-like computer simulations.
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Matthias Heilweck,David Moore, William Burton Fears,Peter Petros, Samuel James Squires,Elena Tamburini, Robert Paul Waldron
Vide Leaf, Hyderabad eBooks (2023)
Sustainable development goals seriespp.217-242, (2022)
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