Research
Our research is focused on the prediction and design of protein structures, protein folding mechanisms, protein-protein interactions, protein-nucleotide interactions, and protein-ligand interactions. Our approach is to use experiments to understand the fundamental principles underlying these problems, to develop simple computational models based on these insights, and to test the models through structure prediction and design. We strive to continually improve our methodology by iterating between computational and experimental studies.

Honors
2012 Biochemical Society Centenary Award
2009 Sackler Prize in Biophysics
2008 American Academy of Sciences
2007 Editorial Board, PNAS
2006 National Academy of Sciences
2004 Foresight Institute Feynman Prize
2004 AAAS Newcomb-Cleveland prize
2003 Director, Biomolecular structure and design graduate program (BMSD
2002 International Society for Computational Biology Overton Prize
2000 Protein Society Young Investigator Award
2000 HHMI Assistant Investigator
2000 Editorial Advisory Board, Protein Science
1995 Beckman Young Investigator Award
1994 Packard Fellowship in Science and Engineering
1994 National Science Foundation Young Investigator Award