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Dr. Walker's research interests are broadly in the area of obligately intracellular bacteria that are transmitted by arthropod vectors focused on immune mechanisms against rickettsiae, ehrlichiae and Orientia tsutsugamushi and identification of the protein antigens that stimulate immunity. Although the diseases caused by rickettsiae include many long known and feared life threatening infections such as Rocky Mountain spotted fever and epidemic typhus, elucidation of their molecular composition and effector immune mechanisms remains productive lines of investigation. In contrast, human ehrlichioses are truly emerging infectious diseases that are causing increasingly prevalent, severe infections. Ehrlichial pathogenesis and immunity are in the process of being discovered and investigated at present for these novel organisms. His focus has also added the neglected tropical rickettsial disease, scrub typhus.
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The American journal of tropical medicine and hygieneno. 6 (2024): 1057-1064
Zemin Yang,Bryan A. Johnson,Victoria A. Meliopoulos,Xiaohui Ju,Peipei Zhang,Michael P. Hughes,Jinjun Wu, Kaitlin P. Koreski, Jemma E. Clary,Ti-Cheng Chang, Gang Wu,Jeff Hixon,
CELL REPORTSno. 3 (2024): 113965-113965
Bryan G. Pearson,David H. Walker,Alfred S. Lea,Wissam Khalife, Karen K. Kislingbury,Scott D. Lick,Paul J. Boor
Cardiovascular Pathology (2024): 107661-107661
Hannah C. Kubinski,Hannah W. Despres,Bryan A. Johnson,Madaline M. Schmidt, Sara A. Jaffrani,Margaret G. Mills,Kumari Lokugamage, Caroline M. Dumas,David J. Shirley,Leah K. Estes,Andrew Pekosz,Jessica W. Crothers,
biorxiv(2024)
EMBO REPORTSno. 2 (2024): 902-926
Nature communicationsno. 1 (2023): 4260-13
Álvaro A. Faccini-Martínez,Louise Bach Kmetiuk,Lucas S. Blanton, Laís Giuliane Felipetto,Mara Lúcia Gravinatti,Jorge Timenetsky,Luiz Ricardo Gonçalves, Rosangela Zacarias Machado,Marcos Rogério André,Fabiano Borges Figueiredo,Andrea Pires dos Santos,Marcelo B. Labruna,
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