He is interested in pragmatic, clinically relevant research that can be readily applied to practice to improve patient care and outcomes. He is principal investigator of national multicentre clinical trials aimed at optimizing outcomes for patients with stroke and transient ischemic attack (TIA). His research has been funded by peer-reviewed grants from the Canadian Stroke Network and the Canadian Institutes of Health Research, among others. He has authored or co-authored more than 100 scientific publications spanning the spectrum of stroke care including stroke prevention, prehospital care, emergency treatment of ischemic and hemorrhagic stroke, transient ischemic attacks, cryptogenic stroke, atrial fibrillation, anticoagulant therapies, outcome measures in stroke recovery and neurorehabilitation.