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There are two areas of research in our laboratory: 1.) One is a basic research study that is investigating a general characteristic of cancer development. It is largely a genomics study using molecular biology methodology to study DNA replication origins and regions of DNA replicated at the beginning of S phase. 2.) The second is a translational study concerned with the mechanisms of development of a specific type of cancer: endometrial cancer. We reconstruct human endometrium in culture from its constituent cells and study the interaction between endometrial epithelial and stromal cells that determine normal tissue structure and function. In this system we are attempting to reproduce the progressive steps of endometrial cancer development. These projects are described in greater detail below.
Research Interests
Papers共 53 篇Author StatisticsCo-AuthorSimilar Experts
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Jeremy D. Ward,Mahesh S. Sharma, Matthew F. Pizzuto,Vincent J. Moylan,Frederic B. Askin,David G. Kaufman
CLINICAL PATHOLOGY (2022): 2632010X2210889-2632010X2210889
mag(2013)
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April M. Luke,Paul D. Chastain, Brian F. Pachkowski, Valeriy Afonin,Shunichi Takeda,David G. Kaufman,James A. Swenberg,Jun Nakamura
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