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Research Summary
My research interests lie in how computational approaches can be used to understand the relationship between protein sequence, protein structure and biological function and disease. My research has focused on many aspects of computational structural bioinformatics, including both the development of new algorithms and the application of these techniques to predict the effect genetic sequence variations have on the structure, dynamics, folding and function of proteins and their involvement in the onset and proliferation of disease. I am currently applying these aprroaches to strain variation in the Influenza virus and other infectious diseases.
My research interests lie in how computational approaches can be used to understand the relationship between protein sequence, protein structure and biological function and disease. My research has focused on many aspects of computational structural bioinformatics, including both the development of new algorithms and the application of these techniques to predict the effect genetic sequence variations have on the structure, dynamics, folding and function of proteins and their involvement in the onset and proliferation of disease. I am currently applying these aprroaches to strain variation in the Influenza virus and other infectious diseases.
Research Interests
Papers共 152 篇Author StatisticsCo-AuthorSimilar Experts
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Sarah R. Carrino-Kyker, Anna L. Parker,Juliana S. Medeiros,Charlotte R. Hewins, Glenn R. Novotny, Stephen L. Krebs,David J. Burke
Symbiosisno. 2 (2024): 231-244
EBioMedicine (2024): 105013-105013
Andrew L. Loyd,Richard S. Cowles, Matthew A. Borden,James A. LaMondia, Nathaniel Mitkowski, Heather Faubert,David Burke, Constance Hausman,Daniel Volk, Caitlin Littlejohn,Amber Stiller,Chad M. Rigsby,
Journal of Environmental Horticultureno. 1 (2024): 1-13
bioRxiv the preprint server for biology (2024)
Shufang Fan,Huihui Kong,Lavanya Babujee, Robert Presler, Jr.,Peter Jester,David Burke,David Pattinson, Ian Barr,Derek Smith,Gabriele Neumann,Yoshihiro Kawaoka
EBioMedicine (2024): 105013
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Applied and environmental microbiologyno. 6 (2024): e0014224-e0014224
Nucleic acids research (2024)
Jürgen Jänes, Marc Müller,Senthil Selvaraj,Diogo Manoel,James Stephenson,Catarina Gonçalves,Aleix Lafita,Benjamin Polacco,Kirsten Obernier,Kaur Alasoo,Manuel C Lemos,Nevan Krogan,
bioRxiv : the preprint server for biology (2024)
Silvia Carnaccini,C. Joaquin Caceres, L. Claire Gay,Lucas M. Ferreri,Eugene Skepner,David F. Burke, Ian H. Brown,Ginger Geiger,Adebimpe Obadan, Daniela S. Rajao, Nicola S. Lewis, Daniel R. Perez
JOURNAL OF VIROLOGYno. 10 (2023): e0074323-e0074323
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