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David Adelson is Professor and Chair of Bioinformatics and Computational Genetics, Zhendong Chair of Molecular Traditional Chinese Medicine in the School of Biological Sciences at the University of Adelaide and is also a Xinglin Scholar Professor at Guangzhou University of TCM. Prof. Adelson’s current research also focuses on the non-coding portions of animal genomes, such as regions used to transcribe ncRNAs (piRNAs and lncRNAs) and the computational analysis of repetitive, so called “Junk DNA”, in order to understand large scale evolutionary/structural changes in animal genomes. Prof. Adelson has led the analysis of repetitive DNA for the cow, horse and elephant genome sequencing consortia and his lab has recently finished working on the Tuatara repetitive DNA analysis for that international genome sequencing consortium. In addition to characterising repeat content in genomes, his lab continues to develop a set of tools to identify and annotate transposable elements and segmental duplications “from scratch” and to use long read sequencing technology to identify somatic structural variants.. Additional aspects of the genome evolution work include understanding the impact of horizontal transfer of repetitive elements in higher organisms.
Prof. Adelson is currently Director of the Zhendong Centre of Molecular Traditional Chinese Medicine. The philosophy of the Zhendong Centre is that complex molecular effects of TCM preparations will provide a molecular basis for understanding the mode of action of TCM and support integration into Western medicine. A major approach to this work uses transcriptome analysis to identify entire pathways or co-expression sub-networks in cancer cells that are altered as a result of a particular TCM preparation, Compound Kushen Injection.
Prof. Adelson is also Co-Director (with Prof Gary Glonek) of the Bioinformatics Hub, a core facility for bioinformatics training and analysis that serves the research community of The University of Adelaide.
Research:
1)understanding how transposable elements affect genome structure and function at both the individual and species level and 2)using systems biology and network based methods to understand the molecular mode of action of complex mixtures of bioactives such as Traditional Chinese Medicines.
Prof. Adelson is currently Director of the Zhendong Centre of Molecular Traditional Chinese Medicine. The philosophy of the Zhendong Centre is that complex molecular effects of TCM preparations will provide a molecular basis for understanding the mode of action of TCM and support integration into Western medicine. A major approach to this work uses transcriptome analysis to identify entire pathways or co-expression sub-networks in cancer cells that are altered as a result of a particular TCM preparation, Compound Kushen Injection.
Prof. Adelson is also Co-Director (with Prof Gary Glonek) of the Bioinformatics Hub, a core facility for bioinformatics training and analysis that serves the research community of The University of Adelaide.
Research:
1)understanding how transposable elements affect genome structure and function at both the individual and species level and 2)using systems biology and network based methods to understand the molecular mode of action of complex mixtures of bioactives such as Traditional Chinese Medicines.
Research Interests
Papers共 221 篇Author StatisticsCo-AuthorSimilar Experts
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EMBO REPORTSno. 2 (2024): 796-812
Theodore S Kalbfleisch, Stephanie D McKay,Brenda M Murdoch,David L Adelson, Diego Almansa-Villa, Gabrielle Becker, Linda M Beckett, María José Benítez-Galeano, Fernando Biase, Theresa Casey, Edward Chuong, Emily Clark,
Nature geneticsno. 8 (2024): 1566-1573
BIOMEDICINE & PHARMACOTHERAPY (2024): 116767-116767
Mobile DNAno. 1 (2024): 1-8
biorxiv(2024)
Ruby Oberin,Sigrid Petautschnig,Ellen G Jarred,Zhipeng Qu,Tesha Tsai,Neil A Youngson, Gabrielle Pulsoni,Thi T Truong, Dilini Fernando,Heidi Bildsoe,Rheannon O Blücher,Maarten van den Buuse,
eLife (2024)
Developmental cellno. 13 (2023): 1206-1217.e4
Denghao Wu,James Zuiani,Christopher Drogemuller,Sunita De Sousa,David Adelson,David J. Torpy, Patrick Toby H. Coates
TRANSPLANTATIONno. 10 (2023): 140-140
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Author Statistics
#Papers: 218
#Citation: 8537
H-Index: 51
G-Index: 89
Sociability: 7
Diversity: 4
Activity: 35
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