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Research Abstract
Lung cancer is the leading cause of death from cancer in the United States. Better understanding of oncogenes and tumor suppressor genes involved in lung cancer hold the promise of improving clinical care of afflicted patients.
Prior work from our group has focused on transcription factors involved in lung cancer and mechanisms of sensitivity/resistance of oncogene kinases (such as EGFR, ALK, ROS1, MET, BRAF, RET, ERBB2, NTRK, KRAS among others) to tyrosine kinase inhibitors in non-small-cell lung cancer.
Our group is also part of the clinical research effort at Dana-Farber/Harvard Cancer Center (DFHCC), with a focus in lung cancer, tumor genomic biomarkers and immune checkpoint inhibitors. We are supported by both federal and non-federal grants, and were part of the previously funded NIH/NCI SPORE in Lung Cancer at DFHCC.
One of the main focuses of the DFHCC Lung Cancer Program, in conjunction with the Cancer Clinical Trials Office (CCTO) at Beth Israel Deaconess Medical Center (BIDMC), is to conduct clinical trials that will establish the future evidence-based strategies to manage local, locally advanced and advanced lung cancers.
Research Interests
Papers共 456 篇Author StatisticsCo-AuthorSimilar Experts
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MAGNETIC RESONANCE IMAGING CLINICS OF NORTH AMERICAno. 1 (2024): 171-179
Debora Z Recchimuzzi,Alberto Diaz de Leon,Ivan Pedrosa, Debbie Travalini, Heather Latin,Kenneth Goldberg,Xiaosong Meng, Jovan Begovic, Jesse Rayan,Claus G Roehrborn,Neil M Rofsky,Daniel N Costa
Radiographics : a review publication of the Radiological Society of North America, Incno. 2 (2024): e230142-e230142
RADIOLOGIC CLINICS OF NORTH AMERICAno. 1 (2024): 109-120
Patient Education and Counseling (2024): 108251-108251
Lauriane Giguère,Brittany Mutsaers,Cheryl Harris,Allan 'Ben' Smith, Gerald M Humphris,Daniel Costa,Cary S Kogan,Sébastien Simard,Sophie Lebel, FORWARDS
Psycho-oncologyno. 6 (2024): e6364-e6364
JOURNAL OF PEDIATRIC PSYCHOLOGYno. 1 (2024): 13-26
Urologic Oncology: Seminars and Original Investigations (2024)
JTO CLINICAL AND RESEARCH REPORTSno. 1 (2024): 100614-100614
Urologic Oncology: Seminars and Original Investigations (2024)
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Author Statistics
#Papers: 431
#Citation: 27424
H-Index: 66
G-Index: 161
Sociability: 8
Diversity: 0
Activity: 4
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