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The Colón-Ramos lab is interested in how synapses are precisely assembled to build the neuronal architecture that underlies behavior. To address this, they developed tools in the thermotaxis circuit of C. elegans. Their system enables unbiased genetic screens to identify novel pathways that instruct synaptogenesis in vivo, and single-cell manipulation of these pathways to understand how they influence behavior. As mechanisms underlying synapse structure and function are conserved, the research program seeks to enhance our understanding of synaptic cell biology in higher organisms, which may be important for disease.
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Cell Reportsno. 4 (2024): 114042-114042
Autophagyno. 10 (2023): 2807-2808
Min Guo,Yicong Wu,Yijun Su,Shuhao Qian, Eric Krueger,Ryan Christensen, Grant Kroeschell, Johnny Bui, Matthew Chaw, Lixia Zhang,Jiamin Liu, Xuekai Hou,
bioRxiv the preprint server for biology (2023)
Elizabeth Ransey,Kirill Chesnov, Gwenaëlle E. Thomas,Elias Wisdom,Agustin Almoril-Porras,Ryan Bowman, Tatiana Rodriguez,Elise Adamson,Kathryn K. Walder-Christensen,Dalton Hughes,Hannah Schwennesen,Stephen D. Mague,
Alison Kochersberger,Mohammad Mahdi Torkashvand,Dongyeop Lee,Saba Baskoylu,Titas Sengupta,Noelle Koonce,Chloe E Emerson, Nandan V Patel,Daniel Colón-Ramos,Steven Flavell,H Robert Horvitz,Vivek Venkatachalam,
bioRxiv : the preprint server for biology (2023)
bioRxiv : the preprint server for biology (2023)
bioRxiv : the preprint server for biology (2023)
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