基本信息
views: 286
Career Trajectory
Bio
Haber's laboratory interests have focused on the area of cancer genetics, including the etiology of the pediatric kidney cancer Wilms tumor and genetic predisposition to breast cancer. Recently, his laboratory reported that lung cancers with activating mutations in the epidermal growth factor receptor (EGFR) define a subset of "nonsmokers' lung cancer" that are uniquely sensitive to new targeted therapies that target this receptor (tyrosine kinase inhibitors including erlotinib (Tarceva) and gefitinib (Iressa)). This observation has had important implications for the genotype-directed treatment of non-small cell lung cancer, and more broadly for strategies to identify critical genetic lesions in cancers that may serve as an "Achilles heel" and be suitable for molecular targeting. In a collaboration with MGH bioengineering professor Dr. Mehmet Toner, Dr. Haber’s group has recently established the application of a novel microfluidic technology for quantifying and purifying rare circulating tumor cells (CTCs) from the blood of patients with various epithelial cancers. This new application has potentially profound implications for early diagnosis of cancer and for noninvasive molecular profiling of cancers during the course of therapy.
Research Interests
Papers共 594 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
时间
引用量
主题
期刊级别
合作者
合作机构
biorxiv(2024)
Joseph L. Yellin,Aliya G. Feroe, Ian T. Watkins, Helena Franco,Borna Guevel,Daniel B. Haber,Mininder S. Kocher
JOURNAL OF CHILDRENS ORTHOPAEDICSno. 2 (2024): 208-215
Adam A Friedman,Arnaud Amzallag,Iulian Pruteanu-Malinici, Subash Baniya,Zachary A Cooper,Adriano Piris, Leeza Hargreaves,Vivien Igras,Dennie T Frederick,Donald P Lawrence,Daniel A Haber,Keith T Flaherty,
Avanish Mishra, Shih-Bo Huang,Taronish Dubash,Risa Burr,Jon F Edd,Ben S Wittner, Quinn E Cunneely, Victor R Putaturo, Akansha Deshpande, Ezgi Antmen,Kaustav A Gopinathan,Keisuke Otani,
bioRxiv : the preprint server for biology (2024)
Philip J Saylor,Keisuke Otani, Rene Balza,Jacob Ukleja,Haley Pleskow, Rebecca Fisher, Erika Kusaka,Yukako S Otani, Priscilla Oluwakemi Badusi,Matthew R Smith, Erika Meneely,Kara Olivier,
JCO precision oncology (2024): e2300230-e2300230
Science (New York, N.Y.)no. 6681 (2024): 368-370
crossref(2023)
JCO precision oncology (2023): e2200532-e2200532
crossref(2023)
Cancer Researchno. 2_Supplement_2 (2023): IA010-IA010
Load More
Author Statistics
Co-Author
Co-Institution
D-Core
- 合作者
- 学生
- 导师
Data Disclaimer
The page data are from open Internet sources, cooperative publishers and automatic analysis results through AI technology. We do not make any commitments and guarantees for the validity, accuracy, correctness, reliability, completeness and timeliness of the page data. If you have any questions, please contact us by email: report@aminer.cn