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Bio
Daniel Aberdam received his PhD from the Weizmann Institute of Sciences (Rehovot, Israel) under the supervision of Prof. Leo Sachs. He has been recruited at INSERM (France) as Director of Research in 1995 and served as head of INSERM unit in Nice and more recently in Paris. He became an expert in skin pathophysiology and more particularly on genodermatoses. He participated in the discovery of genes responsible for epidermolysis bullosa syndromes and used pluripotent stem cells to recapitulate skin and cornea embryonic development to identify both major molecular actors involved and potential therapeutic tools. It allowed more recently his team to demonstrate that a repurposed drug applied topically is able to treat severe skin erosions in ectodermal dysplasia patients. His team has furthermore modelized aniridia-associated keratopathy (AAK) in vitro by gene editing and identified small compounds able to rescue in vitro the pathological phenotype. In collaboration with partners of Aniridia COST and EU network, his team aims at understanding the mechanism of action of these drugs and validating in vivo these potential therapeutic compounds to treat AAK in patients.
Research Interests
Papers共 177 篇Author StatisticsCo-AuthorSimilar Experts
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Clement Berthy, Laurent Gagnoux- Palacios,Marine Madrange, Christine Bodemer,Nicolas Cagnard, Smail Hadj-Rabia,Isabelle Petit,Daniel Aberdam
JOURNAL OF INVESTIGATIVE DERMATOLOGYno. 3 (2024): 717-719
Lubov Turovsky, Ghazal Kheshaiboun,Gharam Yassen, Sara Nagosa,Ilanit Boyango,Aya Amitai-Lange,Swarnabh Bhattacharya,Neta Ilan,Israel Vlodavsky,Daniel Aberdam,Ruby Shalom-Feuerstein,Emily Avitan-Hersh
Cell Death & Diseaseno. 2 (2024): 1-10
Lubov Turovsky, Ghazal Kheshaiboun,Gharam Yassen, Sara Nagosa,Ilanit Boyango,Aya Amitai-Lange,Swarnabh Bhattacharya,Neta Ilan,Israel Vlodavsky,Daniel Aberdam,Ruby Shalom-Feuerstein,Emily Avitan-Hersh
CELL DEATH & DISEASEno. 2 (2024)
Survey of ophthalmologyno. 2 (2024): 300-301
STEM CELL REPORTSno. 12 (2023): 2313-2327
Clément Berthy,Laurent Gagnoux-Palacios,Marine Madrange, Christine Bodemer,Nicolas Cagnard, Smail Hadj-Rabia,Isabelle Petit,Daniel Aberdam
The Journal of investigative dermatologyno. 3 (2023): 717-719
Tanja Ilmarinen,Meri Vattulainen, Jeyalakshmi Kandhavelu, Dominique Bremond-Gignac,Daniel Aberdam,Heli Skottman
STEM CELLSno. 8 (2023)
Cellsno. 4 (2023): 617-617
biorxiv(2023)
Survey of ophthalmologyno. 5 (2023): 940-956
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