基本信息
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Bio
The Huryn lab is a medicinal chemistry and chemical biology laboratory. We focus on the design and design and synthesis of small molecule probes and potential therapeutics to understand and eventually treat diseases for which there is an unmet medical need, including acute kidney injury, muscular dystrophy, and rare neurodegenerative disorders, among others. We have a particular interest in modulating epigenetic processes and have several projects targeting histone deacetylases and bromodomains. We work closely with collaborators in biology, computational chemistry and related disciplines to advance projects.
Students in the Huryn lab become proficient in modern organic synthesis, medicinal chemistry and drug discovery. They develop an understanding of biochemistry and biology, and use modern spectroscopic and analytical techniques. There are also opportunities to work in collaborators’ labs to learn novel techniques and skills.
Students in the Huryn lab become proficient in modern organic synthesis, medicinal chemistry and drug discovery. They develop an understanding of biochemistry and biology, and use modern spectroscopic and analytical techniques. There are also opportunities to work in collaborators’ labs to learn novel techniques and skills.
Research Interests
Papers共 162 篇Author StatisticsCo-AuthorSimilar Experts
By YearBy Citation主题筛选期刊级别筛选合作者筛选合作机构筛选
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Edward Chuang,Ryan R. Cupo, Jeffrey R. Bevan,Mikhaila L. Rice,Shuli Mao, Erica L. Gorenberg,Korrie L. Mack,Donna M. Huryn,Peter Wipf,Jeffrey L. Brodsky,James Shorter
biorxiv(2024)
Purbasha Nandi, Kira DeVore,Feng Wang,Shan Li, Joel D Walker, Thanh Tung Truong, Matthew G LaPorte,Peter Wipf, Heidi Schlager, John McCleerey, William Paquette, Rod Carlo A Columbres,
Communications chemistryno. 1 (2024): 177-177
Bioorganic & Medicinal Chemistry Letters (2024): 129810-129810
Organic Process Research & Developmentno. 20 (2023): 14257-14263
Matthew G LaPorte,Celeste Alverez, Alexander Chatterley,Marina Kovaliov,Evan J Carder, Michael J Houghton,Chaemin Lim,Eric R Miller,Lalith P Samankumara,Mary Liang,Kaylan Kerrigan,Zhizhou Yue,
ACS medicinal chemistry lettersno. 7 (2023): 977-985
ACS INFECTIOUS DISEASESno. 10 (2022): 1975-1980
Keith Long, Zoe Vaughn, Michael David McDaniels,Sipak Joyasawal,Aneta Przepiorski,Emily Parasky,Veronika Sander,David Close,Paul A Johnston,Alan J Davidson,Mark de Caestecker,Neil A Hukriede,
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Author Statistics
#Papers: 164
#Citation: 5132
H-Index: 33
G-Index: 69
Sociability: 7
Diversity: 0
Activity: 1
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