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Research Summary
Drugs and Diagnostics for parasitic diseases of poverty
Parasitic diseases associated with poverty, including the neglected tropical diseases, are overlooked in terms of the number, efficacy and safety of the drugs available for treatment. As part of the Center for Discovery and Innovation in Parasitic Diseases (CDIPD), and with a focus on schistosomiasis, African trypanosomiasis and hookworm disease, three broad themes underpin my team’s research: (1) the identification and validation of protein targets for drug development; (2) the pre-clinical and translational development of drugs, including the development and application of associated technologies (high-content and high-throughput screening platforms, Machine Learning, protein expression and animal models of infection); and (3) the development of point-of care (POC) diagnostics. To facilitate our cross-disciplinary research interests, my team collaborates with academia and the pharmaceutical industry worldwide, including with bioinformaticians, medicinal and clinical chemists, structural biologists and automated systems specialists. Finally, with international partners, my team is actively engaged in training and capacity-building with researchers from low-/middle-income countries to translate drug discovery practices and technologies back to their home institutions.
Research Interests
Papers共 210 篇Author StatisticsCo-AuthorSimilar Experts
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Andrew Spaulding,Amrita Sharma,Miriam A Giardini,Benjamin Hoffman,Jean A Bernatchez,Laura-Isobel McCall,Claudia M Calvet,Jasmin Ackermann,Julia M Souza,Diane Thomas,Caroline C Millard,William G Devine,Baljinder Singh, Everton M Silva,Susan E Leed,Norma E Roncal, Erica C Penn,Jessey Erath, Gaurav Kumar,Yadira Sepulveda,Arnold Garcia,Ana Rodriguez,Nelly El-Sakkary,Richard J Sciotti,Robert F Campbell,Jeremiah D Momper,James H McKerrow,Conor R Caffrey,Jair L Siqueira-Neto,Michael P Pollastri,Kojo Mensa-Wilmot,Lori Ferrins
ACS infectious diseasesno. 3 (2025): 584-599
Mercedes Rubio-Hernandez, Thaiz R. Teixeira, Tina P. Nguyen, Mai Shingyoji,Elany Barbosa da Silva,Anthony J. O'Donoghue,Conor R. Caffrey,Silvia Perez-Silanes, Nuria Martinez
biorxiv(2025)
Jessica Alves Nunes,Paulo Fernando da Silva Santos-Junior, Midiane Correa Gomes, Luiz Alberto Santos Ferreira, Emanuelly Karla Araujo Padilha,Thaiz Rodrigues Teixeira, Emily J. Stanger, Yashpreet Kaur,Elany Barbosa da Silva,Clara Andrezza Crisostomo Bezerra Costa,Johnnatan Duarte de Freitas,Joao Xavier De Araujo-Junior,Francisco Jaime Bezerra Mendonca-Junior,Miriam A. Giardini,Jair L. Siqueira-Neto,Conor R. Caffrey,Peng Zhang,Silvia Helena Cardoso,Edeildo Ferreira da Silva-Junior
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2025)
bioRxiv the preprint server for biology (2024)
Emmanuel Oluwadare Balogun, Gideon Ibrahim Joseph, Samuel Charles Olabode, Naziru Abdulkadir Dayaso,Ammar Usman Danazumi,Rachael Bashford-Rogers,James H. Mckerrow,Ghulam Jeelani,Conor R. Caffrey
PATHOGENSno. 10 (2024)
Lizandra Guidi Magalhães Caldas,Lucas A. L. Paula,Sérgio R. Ambrósio, Jairo K. Bastos,Yujie Uli Sun,Conor R Caffrey, Lizandra Guidi Magalhães
Simpósio Internacional sobre Esquistossomose (2024)
Ameera Mohammed Dawoodjee, John Sichinga, Harrison Banda, Steve Mbaya,Evelyn Funjika,Godfrey Mayoka,Christabel Hikaambo,Karol R. Francisco,Yujie Uli Sun,Lawrence J. Liu,Conor R. Caffrey,Peter Mubanga Cheuka
Pavla Fajtova,Brianna M. Hurysz,Yukiko Miyamoto,Mateus Sa M. Serafim,Zhenze Jiang, Julia M. Vazquez,Diego F. Trujillo,Lawrence J. Liu, Urvashi Somani,Jehad Almaliti,Samuel A. Myers,Conor R. Caffrey,William H. Gerwick,Dustin L. Mcminn,Christopher J. Kirk,Evzen Boura,Lars Eckmann,Anthony J. O'Donoghue
PROTEIN SCIENCEno. 12 (2024)
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Author Statistics
#Papers: 210
#Citation: 9396
H-Index: 49
G-Index: 92
Sociability: 7
Diversity: 4
Activity: 28
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